The Cell- Based Human Proteome Project | Neil Kelleher | TEDxNorthwesternU

Neil's TEDx Talk, A Plan to Weigh Every Protein in the Human Body: The Cell- Based Human Proteome Project presents a "big science" project with huge implications for how proteins in the human body are catalogued and used for drug therapies and treatments.

Since 2011, Dr. Kelleher has served as the director of the Proteomics Center of Excellence at Northwestern University, where dozens of Northwestern laboratories are supported and beyond state-of-the-art in Top Down proteomics is developed. Dr. Kelleher was elected Treasurer of the American Society for Mass Spectrometry in 2012 and established the Consortium for Top Down Proteomics that same year With more than 200 papers published over the course of his career and teaching duties in two departments, Dr. Kelleher is a trans-disciplinary investigator with visible streaks of international impact in mass spectrometry-based proteomics and the discovery of new natural products from the microbial world. Validation of protein-based biomarkers in organ transplantation and cancers of the blood are among the focused areas currently being pursued in clinical research at Northwestern.

[emhartzog]

Please keep this project going. I wish I could express how important this is...people are dying. Watch strolling under the skin.

[jofoodie]

This is such big news! I hope I live long enough to see this project completed.

[AAAA-gpvk]

why is this not getting as much attention and funding as the human genome project? it is probably as important and impactful i imagine

[motioninmind]

The proteome seems to be exponentially more complex than the genome. It's like comparing the visible universe (genome) to dark energy/matter (proteome). And whereas the genes don't actually *do* anything and are always there where you expect find them, the proteins travel throughout the body and could be causing completely different things depending on what type of cell they dock with. I think the human race won't last long enough to ever actually decode the proteome. But the work should still bring great benefits nonetheless.

[SwanOnChips]

My guess is he would agree that just weighing the proteoforms is just scratching the surface.

[amitcarbyne]

What amino acids is collagen type 1 made of?