Immune Response, Toll Like Receptors (TLR) Pathway - IMGENEX

Watch The second Video in the TLR Series!!!! - Don't for get to Like and Follow!

Toll Like Receptors: The GateKeepers of Innate Immunity

Innate immunity as the first line of defense
The innate immune system is an ancient host defense mechanism found in almost every multicellular organism from plants to humans. In invertebrates it is the sole mechanism of defense against pathogens but in higher vertebrates constitutes the first line of defense. The role of the innate immune system is not an insignificant one; not only must it discriminate between self and non-self as well as distinguish between pathogenic and non-pathogenic microbes, it also plays an important role in triggering and optimizing the adaptive immune response. This remarkable system allows an immediate non-specific response against microorganisms whereas the adaptive immunity mounts a specific response against the invading pathogen during the late phase of the infection.

[killpy]

Absolutely horrifying and inscrutable. I love it, thank you

[Guihlopez]

This video is absolutely amazing. Immunology completely makes sense after watching it. Congratulations to whoever made it.

[Phase]

Believe it or not, I'm currently writing an essay on Toll-like receptor signalling for a coursework and this was the most accessible summary I've found so far. Excellent work!

[yeshitellaaleme]

I watched this 6 years ago and I wanted to watch it again then my mom put out a YouTube video and it popped up I'm crying tears of joy!!

[litojonny]

this is what id imagine what studying immunology high must be like

[rickyroko]

This is the greatest ANIMATION i've ever seen in immunology! lots of love

[Airhockeylirare]

So this is what happens when microbiologists take LSD...

[leticiacuellar]

Kudos to the producers for making this TLR series funky fun!

[Hellos.]

I can only imagine a game designer and a doctor collaborating on this 😂. It’s a wild ride.

[dr.salmanriaz]

what can u expect more than this?...
lovely...thousands of heart loving kisses to the one who created

[juliaskripka-serry]

peeing my pants laughing is definitely not the outcome I was expecting when I youtubed TLR videos today

[HassanKhan-sxnt]

content like this derived people's on youtube to clear concept such videos make study very easy so there is no excuse for no learning

[mindimpulse]

it would have been bestt if there was commentary too .. for explaining the video

[ita]

B7 molecules are B7.1 (CD80) and B7.2 (CD86). They both bind CD28 to sustain T cell activation.

[russelmiller]

vivid explanation on the topic. Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the innate immune system. TLRs generally exist as homodimers (heterodimers have been reported) and are found on immune cells; macrophages, B lymphocytes and mast cells.

[aishabhat]

This is toooo cute, never seen anything so interesting and creative related to my studies.
Thank you so much for this animation❤

[neerajpatil]

Hey! You have uploaded a really nice video. But changes should be made in the names of all component cells and proteins. One can not see properly the names in lower resolutions.

[caslandry]

This is kinds how it feels when I study for my immunology final after a few too many edibles, and maybe some acid.

[Mai]

love the animation! makes it much more fun to watch, especially for someone with a short attention span like me who's trying to study. But you should have someone explaining each process instead of music, that would be much better :D someone with a good cartoon voice.

[areanaangel]

the music was nice tho. i was dancing in my room. lol