Cushing Triad | Reflex | Reaction in raised ICP🩺

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Cushing Triad | Reflex | Reaction in raised ICP🩺

This lecture is a clip from the Blood pressure regulation

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The Cushing reflex (vasopressor response, Cushing reaction, Cushing effect, and Cushing phenomenon) is a physiological nervous system response to acute elevations of intracranial pressure (ICP), resulting in Cushing’s triad of widened pulse pressure (increasing systolic, decreasing diastolic), bradycardia, and irregular respirations. The Cushing reflex was proposed in 1901 by Dr. Harvey Cushing. He believed that the dramatic increase in blood pressure was a reflex to brainstem ischemia seen in patients with increasing ICP from causes such as intracranial hemorrhage, a mass effect from a tumor, and cerebral edema, to name a few. In cases of increased ICP, cerebral perfusion pressure (CPP) drops as the systolic blood pressure cannot overcome the resistance present in the brain. CPP is the pressure that pushes blood through the cerebrovascular network and is defined by the difference between mean arterial pressure (MAP) and intracranial pressure (ICP).

With an acute intracranial pathology that causes a mass effect and increased resistance in intracranial vessels, the only way for the body to perfuse intracranial tissue is through elevating the MAP to restore baseline CPP. Dr. Cushing proposed that systemic vasoconstriction and subsequent rise in systemic blood pressure was a mechanism to overcome increased resistance in the brain, increase the CPP, and prevent further ischemia in the brain.
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This lecture is a clip from the Blood pressure regulation
Complete lecture is available in the members area at: www.DrNajeebLectures.com

DoctorNajeeb
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A.Rehmanjatt
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How respiratory rate in cushing reflex is decreased inspite of high paco2?

mohdabdulrahmanquadri
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mehrinferdousrimo