ACTIVATION trial. PCI before TAVR.

The percutaneous coronary intervention prior to transcatheter aortic valve implantation (ACTIVATION) trial (
#ACTIVATIONtrial) tested the strategy the #PCI before #TAVR Vs #TAVR without #PCI in patients with significant #CAD without significant #angina. Unfortunately the trial was terminated because of slow enrollment. Yet, it shed light on important issue in the holistic management of #TAVR patients. With newer evidences for management for #TAVR patients, more and more people are going to be screened for and offered #TAVR. Management of concomitant #CAD in these patients is an important issue. In this video we discuss about the #ActivationTrial and what to do for #CAD in patients undergoing #TAVR.

Our older discussions
EMPEROR PRESERVED trial

We have discussed about the current status of drugs useful in #heartfailure with preserved ejection fraction in this video.
Treatment of HFpEF

We have discussed the role of SGLT2 Inhibitors in this video.
SGLT2inhibitors in heart failure.

Device related thrombosis after LAA occlusion

Abelacimab for prevention of venous thromboembolism

ADAPTABLE trial. Aspirin for secondary prevention

REHAB-HF trial. Cardiac rehabilitation in heart failure

GALACTIC HF trial. Omecamtiv mecarbil in heart failure

In-stent restenosis

TTM-2 trial. Therapeutic hypothermia in cardiac arrest

FLOWER-MI trial. FFR in STEMI

LAAOS-3 trial. Left atrial appendage occlusion in cardiac surgery

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