Meso Compounds

This organic chemistry video tutorial explains how to draw a meso compound and how to identify them. Meso compounds are achiral molecule with chiral centers. They have an internal plane of symmetry and are superimposable images. Meso compounds are optically inactive and they are identical molecules.

Organic Chemistry - Video Lessons:

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Finding Chirality Centers:

Chiral and Achiral Molecules:

Stereochemistry:

Enantiomers:

Diastereomers:

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Stereoisomers:

Optical Activity & Specific Rotation:

Enantiomeric Excess Test Question:

SN2 SN1 E1 E2 Reaction Mechanisms:

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Alkene Reactions Review:

Alkyne Reactions Review:

Organic Chemistry PDF Worksheets:

Organic Chemistry 1 Exam 2 Playlist:

Full-Length Videos and Worksheets:

[lizzyw]

Thank you! I was about to cry over this! Can’t believe how simple it is!

[choogwalda]

Y'all keep in mind these are Fischer projections. The horizontal lines are assumed to be wedges, coming out of the page towards you.

[mwabakombe]

Thank you very much for this ... imagine sitting in class for 40 minutes without anything but here only ten minutes

[rosnaparvin]

It is really awesome sir...u humbly simplified the complexity of meso compounds..thanks a lot 🥰🥰🤩

[smallypimpy]

This video explained to me what several 2 hour videos couldn't properly.

[Mariiiam]

You constantly save my life every finals

[kareemalabbasi]

That was helpful I used to find it confusing first but this video has disproven my point🙏🏻😁

[venkataabhinav]

Thank you so much tomorrow is my Medical Entrance

[cabreal]

Thank you so much for these videos ❤ they actually helped me get good grades 😍❤😘

[crystaltekate]

THERE IS AN ERROR: the 1-3-cyclobutanediol is not a meso compound because it does not have any chiral centers: the C connected to the hydroxyl groups are not chiral centres because they both attached to two same group of atoms CH2-CH-0H. We can however say that it is a cis compound (both OH groups point on the same direction).

[Johan]

At 7:15, the cyclobutane with the OHs, isn't that not a meso compoud since it doesn't have chiral centers? carbons are attached to the same thing on both sides/symmetrical. Wouldn't it just be achiral and not meso?

[billyjoe]

The one on the bottom left of the of the worked examples is not a chiral molecule. Both carbons connected to the carbons with the OHs have the exact same connectivity rendering the those carbons achrial.

[anthonyfigueroaa]

In short. If there is a line of simmetry and chiral centers it is a mesocompound.

[priyankamohanty]

Bravo sir🥰....loved it.. clearly mentioned

[lucasmontagne]

Thanks a lot mate, was really helpful - best wishes from Denmark :)

[gkanastasia]

6:44 I'm confused with this example that doesnt have chiral centers but has an internal line of symmetry. I thought meso compounds need to have two or more chiral centers?

[shreyanshuyadav]

That just really cleared my head, thanks brother:)

[michaelmaida]

At 3:45, couldn't the bond going through the dotted red line rotate 180 degrees, causing the compound to have symmetry?
EDIT: Nevermind, I think I understand now. The way I learned these projections are *with* the wedges, but after drawing the projections with the assumed wedges and rotating the bond 180 degrees, it makes sense.

[muhammadjamilu]

There is something wrong with the R and S configuration.R is for clockwise direction band s for anti clockwise direction

[alexandralong]

The cyclobutane ring with 2 OH is not a meso compound. Because the requirement for meso compound is to have at least 2 chiral center. Where chiral center means 4 different group attached. Here the 2 Carbons with OH only have 3 groups attached.