Diabetic Retinopathy, Neuropathy & Cataract | Sorbitol (Alditol) & Osmosis | Clinical Biochemistry

Sorbitol (Alditol)- A sugar alcohol that can damage your eye lens (Cataracts), Schwann cell (Neuropathy), Pericytes (Retinopathy) In Diabetes…Diabetic retinopathy (eye disease in diabetes mellitus), diabetic peripheral neuropathy (sensory-tingling and numbness in patients with high blood sugar). Cataract (damaged eye lens by osmosis) in diabetes. Sorbitol has multiple hydroxyl groups (OH-), therefore hydrophilic, and attracts water into the eye lens by osmosis, leading to damage to the eye lens (cataracts- the lens become opaque).

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[blopblop]

Phew lucky for the biochemistry playlist, most of us arent good at metabolic diseases, so this is amazing !!

[waelfadlallah]

A new clinical biochemistry playlist 🎉
It doesn't get any better than that 👏

[pedrovieira]

Brilliant video!! I a definitly going to check the full playlist

[thesc]

I love your videos, your way and passion, God bless you

[saiteja]

Do a separate video on peripheral neuropathy.(Medicosis is an emotion)

[queenglowiey]

Who else is gonna explain like this? Good question! 💯

[mawadamarei]

2:30 This is amazing! I've never known this and I was often mixing them up!
1:52 I have a question here.. So, Sorbitol is osmotically active that's how cataract happens, isn't Glucose osmotically active too?
5:10 😂😂

[alanwaterman]

Where does the reduction reaction occur, in the blood or tissue? How does the sorbitol diffuse into the tissue against it's concentration gradient. What about the osmotic gradient?

[medicobhowmik]

Amazing! Best ever teacher I found in you tube..🫡🫡🫡

[arbiankarim]

Oh my god this explanation is so clear and concise 😭. Thank you so much doctor!!

[marcusmiyata]

As a diabetic type 2 with retinopathy undergoing treatment ( 6 times anti vegf injections ) I am very surpised to discover right now, that my sweetener can be the culprit for my condition, for it sorbitol content! Thar could be the reason for my retinopathy being so persistent to present date even with ha1c in the middle 5. Hpe that with no sorbitol on my foods, the condition could improve.

[hypnosisforhappiness]

Can sorbitol cause cataracts too in someone who doesn't have diabetes?

[namangupta]

Does a similar thing happen if one consumes erythritol or xylitol?

[adlyaboamra]

hi sir What medicine can be given to a patient when there is too much sorpitol in his blood?

[Katt-w]

How long does pneumonia last in healthy person for?

[angeliclight-hh]

what is the bestsweetner no stevia no allulose

[manmohansinghrao]

5:08 Why does he cusses the professors in every video. It seems like he has some personal grudges. 🤔