NCBI Minute: Using organism (taxonomic) information with standalone BLAST

Presented May 15, 2019.
Limiting a BLAST search to particular organism or taxonomic group is important for making BLAST searches efficient. This also produces results that are easier to interpret especially as the databases continue to grow in size. The latest version of the standalone BLAST databases (BLASTDBv5) have built-in taxonomy information and provide faster sequence access through identifiers. Using Taxonomy limits in your searches is easier than ever when you use these new databases with the current BLAST programs. Through this webinar you will learn how to download and use BLASTDBv5 and the new BLAST programs to limit searches to taxonomic groups and to retrieve sequences from the database by taxonomy without the often difficult step of first downloading an identifier list.

For more help, see:

[shahid.baloch]

Very informative.
Basics covered very well.
Really appreciate your efforts.
Please keep on sharing such useful stuff.

Thanks.

[zoeprincipal]

NO-1886 inhibits size of adipocytes, fact is this is understed and I believe it could still be part of it.
Abstract

Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their presence is associated with increased risk for hospitalization, longer length of stay and all-cause and CVD-related mortality. The economic burden associated with CVD in this population is considerable and the cumulative cost of treating comorbidities may even exceed that of treating COPD itself. Our understanding of the biological mechanisms that link COPD and various forms of CVD has improved significantly over the past decade. But despite broad acceptance of the prognostic significance of CVDs in COPD, there remains widespread under-recognition and undertreatment of comorbid CVD in this population. The reasons for this are unclear; however institutional barriers and a lack of evidence-based guidelines for the management of CVD in people with COPD may be contributory factors. In this review, we summarize current knowledge relating to the prevalence and incidence of CVD in people with COPD and the mechanisms that underlie their coexistence. We discuss the implications for clinical practice and highlight opportunities for improved prevention and treatment of CVD in people with COPD. While we advocate more active assessment for signs of cardiovascular conditions across all age groups and all stages of COPD severity, we suggest targeting those aged under 65 years. Evidence indicates that the increased risks for CVD are particularly pronounced in COPD patients in mid-to-late-middle-age and thus it is in this age group that the benefits of early intervention may prove to be the most effective.

Keywords: COPD; cardiovascular disease comorbidities; cardiovascular disease risk management; chronic obstructive pulmonary disease.

[mathewstorey]

Huge fan!. Thanks for doing these vids, they are very useful. With all respect, it's 2019, why is the sound quality so low? It makes listening a bit of a chore.

[MrRohit]

Can anyone help me connect to someone from marketing team - Regarding media buying.

[basimbasim]

Hello everyone
Please send me you tube link about how to build gentic tree

[randyperaza]

IKEA has no Mindescreationz and I don't feel with my fingers but with my heart