Restrictive Lung Diseases | Clinical Medicine

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Ninja Nerds!
Professor Zach Murphy will be presenting on Restrictive Lung Disease. We will be going into detail on the following main objectives:

1. Definition and Classification of Restrictive Lung Disease
- Gain insights into what constitutes restrictive lung disease and how it varies from obstructive lung conditions.
- Acquaint yourself with the classifications based on etiology, such as intrinsic lung diseases (interstitial lung disease, fibrosis) and extrinsic factors (pleural diseases, neuromuscular disorders).

2. Pathophysiology and Etiologies
- Explore the underlying mechanisms contributing to restrictive lung disease, ranging from inflammation and fibrosis to pleural effusions and chest wall deformities.
- Understand the altered lung mechanics and its relationship to the various causative factors.

3. Clinical Manifestations and Presentation
- Learn to recognize the signs and symptoms commonly associated with restrictive lung disease, such as dyspnea, reduced exercise tolerance, and dry cough.
- Identify potential indicators of severity, such as hypoxia, tachypnea, and the use of accessory respiratory muscles.

4. Diagnostic Criteria and Tools
- Understand the roles and interpretations of various diagnostic tests, including pulmonary function tests (PFTs), high-resolution computed tomography (HRCT), and lung biopsy.
- Familiarize yourself with the latest guidelines for diagnosing restrictive lung disease as outlined by professional bodies like the American Thoracic Society.

5. Initial Management Strategies
- Discuss evidence-based approaches for initial symptom management, such as oxygen supplementation and corticosteroids.
- Learn about the importance of supportive therapies, including physiotherapy and pulmonary rehabilitation, in enhancing quality of life.

6. Definitive Management Approaches
- Examine the various treatment options available, ranging from pharmacological interventions like antifibrotic agents to surgical procedures like lung transplantation.
- Evaluate the risks and benefits of each approach, grounded in the latest research and guidelines.

7. Complications and Prognosis
- Gain an understanding of the potential complications arising from untreated or improperly managed restrictive lung disease, such as respiratory failure and pulmonary hypertension.
- Discuss the prognostic indicators and how variables like age, lung function, and comorbidities may influence outcomes.

Table of Contents:
0:00 Lab
0:07 Restrictive Lung Disease Introduction
0:37 Pathophysiology | Intrinsic Lung Diseases
8:07 Pathophysiology | Extrinsic Lung Diseases
11:45 Complications | Respiratory Failure
15:52 Complications | Cor Pulmonale
19:42 Complications | Lung Cancer
21:55 Diagnostic Approach
27:11 Treatment
29:29 Comment, Like, SUBSCRIBE!

Retired Ninja Nerd Lectures:

#ninjanerd #respiratory #restrictivelungdiseases
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Prophet Mohammed ﷺ said : ‘Whoever does not thank people has not thanked Allah (Most High) . so thanks alot for your hard work 🥰🦾

abdulrhmansamir
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zack and the ninja nerd crew deserve honorary doctorates in education for all they've done

WasabiSniffer
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Thank you so are many people in the medical field's lifesaver!

onesummerday
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Love it, ,
Btw Is this 63 video cover whole medicine💊?

sawantiparang
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"Hypoventilation" is terminology that is generally reserved to mean ventilation is inappropriately low for the carbon dioxide present. These patient's will have an increased PaCO2. Restrictive diseases decrease TLC (in fact are definded by a decreased TLC) but they do not necenssarily cause "hypoventilation". Tidal volumes and respiratory frequency can be normal. Better to say decreased compliance is associated with lower lung volumes.

physiologyWithRobBaer
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thanks so much
thats came in time !!w

SkilloVoice
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Wow, thank you for such an awesome breakdown of lung disease and why how and when of it, I have restrictive lung disease but but what you have explained I think it is from a little bit of all of them. I don’t know how long you need to be exposed to aspestos but my landlord cut a hole in my wall to fit an air conditioner, it was dust from a to b he didn’t cover his lungs nor when he finished did I when I vacuumed it up, then it was in the house I guess being sucked up and spat out again over and over for the time I lived there, and this was 15 years ago. I also used to smoke, I then turned to vapours to get off smoking, it worked but not until the second round and it’s caused sticky fluid into my lungs I’m sure, when I lay down I have wearing and my lungs also have calcified Granuloma, the bottom has traces of old infection, the left middle has collapsed. I have very high arterial blood gases and did have left sided heart failure which seems to have gone away but I have no air on exghaustion, now it’s less and less activity I’m even labouring moving my body in a seated position, I do have a very swollen tummy and edge a feet and legs high blood pressure and cerebral small vessels disease so now I’m on medication three years which has put 36 kg on me which is cause obesety pressure aswel, so when I say I think I have all three you mentioned all my symptoms and yes really bad arthritis, so still I can’t tell which one caused it so don’t know without a Biopsie or further testing what way to treat it. Your not a doctor and I’m so greatful you have helped me understand how the lungs work and how these diseases effects the lungs and why they behave the way they do, the different symptoms etc. in the end you got fast and I had to rewind a couple of times to write it down but your very good at explaining with word and picture. I can now go to my doctors I have a colonoscopy coming up in 7 days and need to explain some things to my anesthesiologist as my New GP only just told me what my old GP was sitting on since February when I had the spirometer test and never said anything yet I suffer every day struggle to breath, it’s getting worse and I need some attention about it, it also explains to me why my body aches so bad after two hours or more of sleep, I’m not getting oxygen to my organs I get headaches and I thought my kidneys weren’t cleaning my blood properly I also have a liver 4 cm bigger than Normal with non alcoholic fatty liver disease which by what your saying the restrictive lung disease can also effect the liver or the liver the lungs, so again, not sure which way started off the bad lungs, need further evaluation thank you for helping me be assertive in asking for what I need to get done.

CheryleaOBrien
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Jai Shree ram aap par Bhagwan Vishnu ki Kripa bani rahe

MadhavSharma-ptsl
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Why do I always feel like taking a long breath and then when I try to take a long breath, why does it get stuck and then yawning continuously? This is a mental as well as a physical problem.😢

AkilaChamod-owhz