Welcome to People's Choice Awards 2012! | E! People's Choice Awards

Host Kaley Cuoco ("The Big Bang Theory") opens the 38th annual show

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The E! People’s Choice Awards celebrates all forms of entertainment, chosen entirely by the fans.

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Welcome to People's Choice Awards 2012! | E! People's Choice Awards

[joyunicycle]

"I don't need to use fireworks when I host. I am the fireworks."
You got that right, Neil! Love you!

[uwillneverknowwho]

"IT'S NOT A GIFT, IT'S A DISEASE!" - I'm dead😂

[Boomabanga]

why is barney acting some guy named neil?

[parisdenise]

I'm in a 12-step program, but I'm only on step FIVE-SIX-SEVEN-EIGHT!

[Hansol]

Big Bang Theory and HIMYM - when two most awesome shows collide, you get priceless stuff like this!

[artyachink]

It's one of a play in his playbook. It's called "The Neil Patrick Harris"

[barneystinson]

dude, i'm awesome! that was legend... wait for DARY! LEGENDARY!

[NiVi]

She actually did really well, and I'm not easy to impress with hosting performances.

[jekufo]

When Neil sayed "oh hey everybody", I waited for "whaDUP?!"

[fennecinspace]

the only genuine laugh and clapping that night were for Neil

[ana-vfhj]

*I ONLY CAME BECAUSE OF NEIL PATRICK HARRIS.*

[GrafEins]

Neil is so amazing! He doesn't even need to say something, I just need to see him and I start smiling :)

[chickennoodlesoup]

"I'm on a 12-step program but im only on 5-6-7-8..." lololol classic

[CelticVolcano]

I like how when the security guys are taking NPH the dancers are dancing their way with him..haha

[PauloSilva-wjqg]

neil patrick is legend wait for it dary

[wipz]

I would love to see them in a sitcom together! XD

[adoringaudience]

I love Kaley on The Big Bang Theory, but as an award show host she was awkward. I cringed the entire time she was hosting. NPH was awesome though, as per usual. EHD seems to work really well for him.

[Meecie]

I love Kaley, but neil just made that scene sooo much awesome

[OTimeMasterXO]

Not gonna lie, as much as i love KC I would have REALLY loved to see that song & dance properly done :D

[DarthJosua]

The red-hair girl next to Neil looks like the french police in Madagascar 3