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Discussion Session by R Srinivasan and Manoj
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DISCUSSION MEETING : THIRSTING FOR THEORETICAL BIOLOGY
ORGANIZERS : Vijaykumar Krishnamurthy and Vidyanand Nanjundiah
DATE : 03 June 2019 to 07 June 2019
VENUE : Ramanujan Lecture Hall, ICTS Bangalore
Experimental biologists frequently point out that theoreticians trivialise the intricacies of living systems, and those working on theories and quantitative models complain that experimenters tend to present masses of data that conflate the essential and the incidental.
A significant element behind this state of affairs is that direct exchanges between researchers who adopt the two approaches are non-existent or rare.
The present discussion meeting aims to address the situation in a small manner by getting experimenters to describe the ways in which they study phenomena and the conclusions that they draw, to a theoretically-minded audience.
The topics to be covered will include the regulation of genetic activity, chromosome dynamics, cytoskeletal organisation, molecular motors, cellular energetics, stem cell behaviour, cell-cell interactions, developmental homeostasis and morphogenesis.
Participation in this meeting is by invitation only.
0:00:00 Discussion Session
0:00:32 Z-ring Force and Cell Shape during Division in Rod-Like Bacteria
0:09:36 Origin of Contractile Force during Cell Division of Bacteria
0:10:38 GTP & GDP
0:18:50 Physical Review Letters
0:21:51 Force Generation by a Dynamic Z-ring in Escherichia coil cell division
0:29:59 Active Curved Polymers Form Vortex Patterns on Membranes
0:36:45 DNA Segregation in Bacteria
0:40:41 Min system
0:42:11 Oscillating foci
0:44:38 Diffusion Ratchet with confinement
0:46:06 A delay in rebinding the chromosomal DNA
0:50:03 An amphipathic helix at the C-termini of SopA
0:51:21 Mutation at C-terminus result in stable cytoplasmic polymers
0:51:51 Membrane association of SopA C-terminus
0:53:44 Mutations at C-terminus prevent binding to chromosomal DNA and affect plasmid stability
0:54:25 A schematic for the role of C-terminus amphipathic helix
0:55:59 Summary so far
0:56:15 A Speculative scheme
1:00:07 Diffusion Ratchet with confinement
ORGANIZERS : Vijaykumar Krishnamurthy and Vidyanand Nanjundiah
DATE : 03 June 2019 to 07 June 2019
VENUE : Ramanujan Lecture Hall, ICTS Bangalore
Experimental biologists frequently point out that theoreticians trivialise the intricacies of living systems, and those working on theories and quantitative models complain that experimenters tend to present masses of data that conflate the essential and the incidental.
A significant element behind this state of affairs is that direct exchanges between researchers who adopt the two approaches are non-existent or rare.
The present discussion meeting aims to address the situation in a small manner by getting experimenters to describe the ways in which they study phenomena and the conclusions that they draw, to a theoretically-minded audience.
The topics to be covered will include the regulation of genetic activity, chromosome dynamics, cytoskeletal organisation, molecular motors, cellular energetics, stem cell behaviour, cell-cell interactions, developmental homeostasis and morphogenesis.
Participation in this meeting is by invitation only.
0:00:00 Discussion Session
0:00:32 Z-ring Force and Cell Shape during Division in Rod-Like Bacteria
0:09:36 Origin of Contractile Force during Cell Division of Bacteria
0:10:38 GTP & GDP
0:18:50 Physical Review Letters
0:21:51 Force Generation by a Dynamic Z-ring in Escherichia coil cell division
0:29:59 Active Curved Polymers Form Vortex Patterns on Membranes
0:36:45 DNA Segregation in Bacteria
0:40:41 Min system
0:42:11 Oscillating foci
0:44:38 Diffusion Ratchet with confinement
0:46:06 A delay in rebinding the chromosomal DNA
0:50:03 An amphipathic helix at the C-termini of SopA
0:51:21 Mutation at C-terminus result in stable cytoplasmic polymers
0:51:51 Membrane association of SopA C-terminus
0:53:44 Mutations at C-terminus prevent binding to chromosomal DNA and affect plasmid stability
0:54:25 A schematic for the role of C-terminus amphipathic helix
0:55:59 Summary so far
0:56:15 A Speculative scheme
1:00:07 Diffusion Ratchet with confinement
1:02:10
1:23:15
0:37:34
0:54:50
0:00:11
0:16:03
0:00:38
0:34:14
0:34:44
1:12:42
0:15:32
0:00:33
0:47:29
0:24:35
1:14:32
0:17:10
1:24:05
0:16:30
0:15:02
0:20:12
0:40:26
0:36:53
0:19:30
0:00:28