49ers vs. Lions Week 1 Highlights | NFL 2021

The San Francisco 49ers take on the Detroit Lions during Week 1 of the 2021 NFL season.

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#NFL #49ers #Lions

[Lycan]

The last two minutes of this game felt like an eternity…. Thanks for giving me heart problems 49ers

[jamesquebral]

First Half: 2019 49ers
Second Half: 2020 49ers

[MYFBL]

Niners were just reminded no matter how badly you're slaughtering the other team, you can't go to sleep. You must always finish!

[SageSea]

Wow this game really was Campbell’s “knock us down, we’ll bite a kneecap” motto

[kennyrichards]

Coming back to this 2 years later as a lions fan after they just got their spot in the nfc title game against the 9ers, I’m just so proud of how far this team has come‼️‼️ GO LIONS

[CarsonClaws]

The lions almost pulled off the greatest comeback in NFL history. They were down 24 with 3 minutes left. Unbelievable effort

[robertbeale]

As a Niner fan I really think both teams won this game. The Lions showed true grit toward the end of the game and The Niners was holding their own while playing on the road. Much respect for both teams.

[doit]

I saw trey lance playing in the first quarter and thought “dammit how is Jimmy already hurt?!?” Lmao

[CrystalDominique]

Who else decided to revisit this matchup for the NFC Championship?

[dengjoe]

The only good thing about this loss is the fact the Packers got beat worse then the Lions did lmao.

[ChiseledAdonis]

Lions came all the way back & came up short... both teams were on the edge of their seats

[elijahnaff]

Jimmy Garoppolo had a great performance for the 49ers. Jared Goff tried to rally, but came up short. So close, but what a performance in his Lions debut.

[Sven_]

From a 49ers fan, that was a heck of a game Lions. Happy to have football back!!

[MS-ujdg]

Im a 9er fan but mannn Penei Sewell is GOOD! He surprised me the most.. He went against 4 different Defensive ends and he had all there numbers! Bosa got that one sack on him but other than that, Penei locked him up! And then they switched Bosa to the other side to try and get more pressure because there was none on Peneis side

[c.pickett]

I love my Detroit Lions' effort...what a great game...I can't wait to lose my voice cheering in the stands for my hometown team! #GoLions

[ninodrago]

i’m a diehard 49ers fan but i give props to the lions for almost making a comeback like that

[amitsuresh]

Oh great the heart attack 49er games from 2019 are back...

[DYNMO]

Being a niner fan is tough when your team tries so hard to give you a heart attack every game 😭😭

[Vallejo]

At this point at the start of 2021, who would of thought that the 49ers were going to play Dan Campbell and this team for a date in the Super Bowl 2 years later?

[nail_fiend]

Wow! I have never seen a Lions team so energized as this 4th quarter team, let's keep that energy up for the rest of the season, boys!!!