What is the Independent-Samples T-Test?

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In this video, we'll discuss the hypothesis test used to test whether the sample means of two different groups differ significantly from one another. This test is known as the independent-samples t-test. We'll also discuss the Cohen's d effect size associated with the independent-samples t-test.
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Maybe it is premature question but is this test relevant for different sample sizes of groups ie. 50 versus 100 samples?

Dr.CandanEsin