Podcast: How genetic testing improves blood cancer detection | OSUCCC – James

Ohio State blood cancer experts are improving outcomes at a new clinic where genetic testing helps raise the chances of vital early diagnoses.

The HALT (Hematologic Abnormalities at risk of Leukemia Transformation) Clinic is a state-of-the-art program designed to detect blood cancers at their earliest — and most treatable — stages.

“The goal is to identify patients or people at higher risk of developing leukemia due to inherited or acquired genetic mutations,” says Uma Borate, MBBS, the co-director of the clinic.

The innovative clinic is made possible by advances in DNA sequencing, which have allowed physicians and other scientists to identify leukemia and other blood cancers in early stages, along with genetic markers that can indicate increased risk.

“We’ve been able to identify patterns of mutations in families and discover inherited genetic disorders we weren’t aware of before,” Borate says.

While the HALT Clinic is relatively new, its building blocks were in place thanks to the continued efforts of OSUCCC – James doctors and researchers. “I helped bring them together under one roof,” Borate says of her role in the clinic’s creation.

Blood cancers can affect people of all ages, though the majority of patients at the HALT Clinic are 60 or older. Borate considers it her mission to help them make the most of their later years.

“That’s what motivates me,” she says. “If we can do something proactively and identify early and intervene, they can enjoy these years — with their grandchildren, traveling — instead of being in my clinic for treatment.”

Learn more about blood cancer, including causes, symptoms and treatment options at Ohio State:

Learn more about cancer care and research at The Ohio State University:

Follow The James on social media:

[rredding]

People, when you own a male reproductive organ, hear me out. I guess that you, just like me, prefer to stay healthy and avoid disease, instead of treating it. So, this is not medical advice, but some things to think over. Beware, this is a long read!
I did my own research (Google, YouTube) and found some factors that influence your future risk for prostate troubles.
One important factor is age! Men above say 50-60 years are most at risk.

1. Deficiency in Iodine. Make sure you get at least 150 micrograms per day, but that is the absolute minimum. Japanse following the traditional diet, may get some 1000 - 3000 micrograms per day, and prostate cancer (also breast cancer for women) is ten times lower than when following the Western diet. If you take Iodine as a supplement, combine this with Selenium. You may get this from having one or two Brazil nuts (also known as Para nuts) daily, not more. Do your own research on these nuts.

2. Deficiency in vitamin K2. This vitamin lowers risk of prostate cancer, AND reduces risk of calcified organs and blood vessels, as it sends Calcium to your bones and teeth. Japanese traditionally eat natto, fermented beans and bacteria produced a lot of vitamin K2. Google vit K2 for yourself.

3.Boron. Boron lowers chances of getting prostate cancer. Many people are deficient in Boron when it is insufficient available in your food. It regulates Calcium and Magnesium, regulates sex hormones in men and women, activates brain activity (memory) AND is anti inflammatory. When you suffer from arthritis, 70% chance that some 9 mg/ day will fight the pain and within 1-3 months the symptoms are gone. Following maintenance dosis is 3-5 mg Boron per day.

4. Many people are deficient in vitamin D3, especially when living outside the tropics, when having dark skin or using sun cream, being senior, obese. D3 regulates many process in your body, and helps to avoid prostate, colon and breast cancer. Do your own research!. Your D3 level in a blood test should be 50-70 ng/ml (125-175 mol/l). When too low, use a good supplement. Guidelines tell you to take 10 or 20 micrograms per day (400 resp. 800 IU) but this is only good to avoid worst effects of deficiency. 10, 000 IU per day is shown to be safe, but always combine with vit K2. A young, white skinned adult with uncovered arms and face will produce some 10, 000-15, 000 IU of vit D3 before burning in, say, 30 minutes. Agsin, don't trust me but do your own research! I took 10, 000 daily for some months and had the blood value tested on the way. I reached 66 ng/ml, a perfect value.

5. If you are low on Zinc, this may harm you. Zinc is important for your genitals. If you are vegetarian or vegan, you probably are deficient in Zinc. Again, please do your own research, gain knowledge on the subject ✌🏻.

6. Cancer cells thrive on sugar. Chances are that you are pre-diabetic or diabetic-2 and not knowing it.. Problem is that your body will produce more and more insulin to get glucose out of the blood and into all cells in your body. Testing glucose won't show the problem until you are really progressed in the process. I know I was careless all my life, because I had a lean body. When I used a CGM (continuous glucose monitor) I knew that my body had a "metabolic syndrome" with peaking glucose values after a high carb meal. Your glucose should not get above 160 (EU: 9), mine peaked at 215 (EU: 12). Again: testing insulin response is better (Kraft test), but not every doctor will test it and it may be expensive. Okay, the cause is in the diet and only changing the diet will help you.... Medicines will only cover the symptoms.. you may start following a low carb (or even keto) diet. A whole plant based diet may be fine as well. This means avoiding sugar, refined carbs (bread, pasta, cookies, fruit juice and sodas) and get your HbA1c down to 4.7-5.5%, triglycerides below 2.5 (USA 85). Also, learn about the processed seed oils (canola, sunflower, sunflower, rapeseed, etc.) Being promoted as much more healthy than animal saturated fats, they promote chronic inflammation and are cause of modern Western disease, inducing cancer. Also read about omega 6:3 ratio's. Chances are that you consume processed, packaged foods, even when you think you about junk food.
Again, don't depend on others, do your own research! 🙏🏻💚