Implementing iPSC derived 3D neurospheroids for fast tracking novel target and hit identification...

Presented By: Cassiano Carromeu, PhD

Speaker Biography: Cassiano Carromeu is the Director of Research and Development at StemoniX and is an expert in neuroscience and stem cell biology. He did his post-doctoral training at UC San Diego using induced Pluripotent Stem Cells (iPSCs) to model autism in vitro and helped to unveil some key aspects of Rett Syndrome and MeCP2 Duplication Syndrome.

Webinar: Implementing iPSC-derived 3D neurospheroids for fast-tracking novel target and hit identification in a human-first drug discovery paradigm

Webinar Abstract: Traditional drug discovery often begins with simple biochemical and transformed cellular models, advances to more complex animal models in late discovery phases, and often does not ‘see’ appropriate human biology until clinical trials. While widely deployed, this process can result in initial hits that do not translate to the clinic and ultimately lead to late-stage failures while running counter to the emerging standard in animal use of replace, reduce, and refine.

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