PRP and PRF 101 #botox #beauty #filler

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🩸Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) are both concentrated growth factors derived from a patient’s own blood.

They differ in their preparation, composition, and clinical applications:

With PRP, The blood is drawn and spun in a centrifuge at a high speed, which separates the blood into different layers. The plasma layer, rich in platelets, is extracted for use.

With PRF, The process is similar, but the blood is spun at a lower speed. This slower centrifugation results in a layer that contains not just platelets but also white blood cells and stem cells, and it forms a fibrin matrix.

Composition:
• PRP: Contains a high concentration of platelets, growth factors, and sometimes anticoagulants to prevent clotting. It does not typically include a fibrin network.
• PRF: Includes a higher concentration of leukocytes (white blood cells) and stem cells, along with platelets and growth factors. It forms a natural fibrin matrix that releases growth factors over time.

Release of Growth Factors:
• PRP: Releases growth factors more rapidly due to the absence of a fibrin matrix.
• PRF: Provides a slower, more sustained release of growth factors due to the fibrin matrix, which degrades slowly over time.

Applications:
• PRP: Commonly used in orthopedics, dentistry, cosmetic facial rejuvenation (such as for treating wrinkles or promoting hair growth), and wound healing.
• PRF: Increasingly used in dental and oral surgery, wound healing, and cosmetic facial rejuvenation. Its sustained release of growth factors and presence of stem cells and white blood cells are believed to enhance healing and regeneration.

Efficacy and Healing:
• PRP: The immediate release of growth factors can jumpstart the healing process.
• PRF: The slower release and presence of additional cellular components are thought to support more effective long-term healing and regeneration.

Anticoagulants:
• PRP: Often contains anticoagulants to prevent clotting.
• PRF: Does not use anticoagulants, allowing the natural fibrin clot to form.


JillCampbellAesthetics
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Prf has no additives but prp does? I’d like to use just my blood only. Is that the right one to choose? Thanks so much for your help!!

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