Antibodies Levels After Vaccination: Moderna Vs Pfizer

There are still a lot of questions about the COVID-19 vaccines. We know that these vaccines are very safe and very effective, even against the delta variant of the coronavirus. Many people have questions about antibody levels after having the vaccine or coronavirus. People want to know if there is a relationship between the level of antibodies and the level of immunity. In this video, we will go over some results from a study that measured the level of antibodies from people who had received the vaccine.
0:00 Questions about COVID vaccines
2:06 New research about antibody levels
3:03 New study from Belgium
3:59 Overall antibody levels for Pfizer and Moderna
6:40 Difference between uninfected and infected patients
8:29 Antibody data by age
9:20 Understanding these results
9:40 Continue to take precautions
12:13 Conclusion

Correction - there is an error in the labels on the second chart showing a comparison of antibody levels for previously uninfected persons vs. previously infected persons. The correct labels are:
1. Previously uninfected: Moderna = 2881 u/ml; Pfizer = 1108 u/ml
2. Previously infected: Moderna = 10708 u/ml' Pfizer = 8174 u/ml

[mickdonedee]

Well presented, sir. You answered all my questions about antibodies. I love that you added, "Continue to take precautions."

[johnchang]

I found this video extremely helpful after having my serology test results. I was able to benchmark that with the Belgium study and reaffirmed my decision to proceed with a booster shot. Thanks for simplifying the Covid test results and making it easy to understand,

[daranou]

Thank you for your service sir. I am so lucky to come across your video. This is a gift to our Humanity

[rawpure]

Its amazing that you have answered so many comments here, you are truly a person that takes his work seriously ^^
Note : i got the Moderna version and i have never heard or met anyone that has gotten covid, i live in sweden.

[janiceperkins]

My latest question is, if they have studied the vaccines enough, why didn't they know how many injections it would take??

[mand]

Very detail and sound explanations, thank you.

[doctorrobert]

I have had two moderna vaccines and had minimal adverse effects. I have read would be best to aspirate before injecting vaccine to make sure no blood vessel was entered to minimize relatively rare heart/coagulation adverse effects. Most vaccine centers do not aspirate and wonder if more studies coming. The few studies were from Europe and hope more standardized procedures are put in place. Thank you for posting this informative video!

[lisalu]

I guess what I want to know - the short answer - is whether I should go ahead and get a Moderna booster based on average data (I'm in my late 50s, and no special health issues.) My second shot was six months ago, and from what I hear the protection - i.e. antibody levels - will begin to wane about that time. Without getting an antibody test, and just going on average response rates, when is the booster recommended for my age group. This was informative, yet hard to extrapolate into a clear answer for that question. (PS... I don't currently have a relationship with a primary care physician, so there is no one to "ask" for their recommendation.)

[reid]

Nicely done, thank you. A question as I'm vaccine hesistant particularly with the limited choices of mRNA cellular level vaccines and their potential long term affects. Would you be able to do a video looking into the likely differences of rMNA, DNA viral vector, and Novovax which I understand is more tradition. I'm happy to get good protection but dosen't have to be at the top of the antibodies list. In my mind it's the long term safety profile that counts more.
Many thanks.

[diegomahoudeau]

Hi Dr.! What health reasons are the ones you are referring to at 8:02? Would like to know some examples, thanks :)

[frankbradford]

This was super useful. And I love when the source data is linked 👍

[janiceolliver]

Interested to note thanks fir this info

[sergeykichuk]

How is on the first chart Overall results was medium of 3836 u/ml and on next slide is 8000 u/ml and 10000I/ml the medium overall should be 9000 u/ml and not 3836?? When you compared vaccinated and not vaccinated??

[dorvilamaya]

I got an antibody test around 3 months after infection and got a 4.97 number from Quest Diagnostics. They indicated that it was high.

[sabehjbara]

Thanks Doctor, valuable information. Dr. What does strongly positive of Polyclonal antibody score +3, and Monoclonal antibody of MIB -1?
A friend diagnosed with breast cancer and she have these numbers of antibody. Thanks.

[myanis]

Is there a study showing level of IgG for recovered covid19 patients who are not vaccinated? .. I would really like to see the range of IgG compared to vaccinated people as you show in this study frm Belgium.

[istanbul]

Hi I found you're video very good and very informative.
My current igg antibody's are still showing 2500 >u/ml 13 months after 2 vaccine doses and don't seem to be dropping below this amount.
Could you tell me any explanation why this would be and does this mean I don't require a 3rd dose of the vaccine if they remain this high ? Thanks

[AlexSmith-grhp]

I get very layman understanding of these things but I’m a bit confused. Am I right in assuming that the T cell response is the longer lasting response that will ultimately be the guide to whether you get reinfection or not, and that you get that response if you’ve had a high B cell response at some point even if that response subsequently wanes. If that’s true or partially true then how much truth is there that the mRNA vaccines are generating B cell responses but not great T cell response, especially compared to natural infection?

[sissysweetp]

Is there any estimate yet from available data on how long the booster shot will provide protection? Is it expected to wane similarly to the 2-dose regimen at around 6 months or will it provide more long-term protection at a higher level? I was fully vaccinated in mid February and trying to be strategic in timing my booster shot for some scheduled travel in April. In the meantime, I am feeling vulnerable and avoiding certain situations where I could be exposed.

[sevenmiller]

Hi can you please explain Dr Richard Flemming nuclear cardiologist work can this we get ADE or cytocline storms. Also what do you think of Dr geert von dussche work is safe to get shot