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Trimethoprim and Sulfamethoxazole combination in PCP

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Trimethoprim and sulfamethoxazole combination is used in the treatment of pneumocystis jirovecii pneumonia previously known as PCP. This is a fungal organism that causes pneumonia in immuno-compromised patients. The two drugs are given in combination at a ratio of 5:1 with sulfamethoxazole at high dose. This combination is well known a co-trimoxazole and familiar under the brand names bactrim and septran.
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