Heart of the Matter: Higher LDL on Keto Does NOT Mean More Plaque.

Chapters
0:00 – Introduction
0:49 – New Publication! LMHR CCTA study
2:58 – Main Findings
7:00 – Perspectives: Clinical Competencies and Translational Outlook
9:51 – Caveats
11:48 – Counter-caveats

Some Other Papers

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[quirkyqs]

Nick, this is fascinating. I’m a physician and have always been curious about the biochemistry on metabolic health. I was on a ketogenic diet in college (about 12-13 years ago before keto was mainstream) based on papers I had read. I was lean and my LDL was also the highest it had ever been, which spooked me. I knew LDL was correlated with heart disease but was curious how it would affect me…obviously I didn’t get a CTA of my coronaries…and stopped the keto diet from fear. Not to mention, the biochemistry and what we learn in medical school support the “badness” of LDL with its coorelation with heart disease. So learning about your work is so exciting as it addressed a question I had about leanness, ketogenic diet, LDL, and heart disease. Preliminary, yes, but we can learn so much still ❤️!

[fjsa_]

53 yo here, close to LMHR, been on keto for about 4 years. Had a CCTA done recently, no evidence of soft/calcified plaque. Go Nick and Dave, your work is important.

Also, just wanted to say that your videos are a joy to watch (minus occasional minor editing issues). You don't use unnecessary words and don't waste time. For my rational/logical brain it's a huge plus. Thank you Nick.

[KenDBerryMD]

Bravo! Chipping away at that paradigm…

[mikecf]

I have been following Dave since back in the day. His work, and yours along with him, are incredible, and what scientists should strive for. Thank you.

[jaymehatfield]

I agree yt must be at work here. Nick, I have followed you and Dave since 2023 when you announced that your study results were going to be announced in Feb-Mar 2024. Thankyou thankyou for your work. Brilliance in America, so RARE.
Nick Norwitz! Go Nick go!!

[roycrossfit]

You guys are doing such an astounding job, both in research and communicating the preliminary results. I can't wait to see you guys get more data over the years. I hope you get the recognition you deserve for this work, which will affect so many.

[colinvankeith]

Thanks Nick, Dave and everybody that made this happen. Just so you know, I have forwarded this study to my doctor and posted on my Facebook.❤

[MichaelWDietrich]

I'm not lean at all ( BMI 34 though rapidly decreasing weight trough low-carb diet), but my bloodwork has shown the same triangle since I went low-carb and controlling my keto status. I've got bloodwork from before where ldl and hdl were in the recomended corridor. First Keto bloodwork from only 3 Months into keto shows nearly doubled ldl and 25% + in hdl where tryclycerides stay low or even dcreased (a not realy significant) bit. This (quaterly measured) trend stayed for the following bloodworks. Though not so dramatic (no doubling of LDL anymore ;-) but still slightly rising LDL while at the same time losing more weight. If I wasn't convinced that Low-Carb and keto had already done a lot of wonders to my health, that LDL-Values would have scared the hell out of me. Glad to find your study.

[llenhu]

Nick- I’m 53, Asian female, have between 350-400 total cholesterol all my life, since I was a teenager. Recently went on carnivore last 6 months and cholesterol is the same, LDL 250, HDL 94 and Tri is 42.

My CAC score is 0. Feel pretty darn good, even with a cholesterol that high for almost 40 years.

Would be happy to be a part of any of your studies or trials.

[ericrichards]

I don't pay a lot of attention to my LDL numbers in my blood work. It usually hovers around 99-105. Instead, I tend to focus on fasting insulin and HbA1c. I have been keto for about a year with great results. Down from 210-170lbs. I am very happy with how I have responded to a ketogenic diet. Love your channel!

[thewrightoknow]

I am a LMHR living in the UK and my DR is always pushing me to take Statins. Great presentation and much appreciated. I am going to send or present this video to my Dr. Blessings!

[younutre]

I have to admit that I can consider myself a "hater" in your videos. But this is mainly due to the way some topics are approached, which I disagree with. However, in this video I have to congratulate you, because you were extremely clear about the nuances and the specific application relative to the studied population. If this theory is proven, it will definitely be a milestone and I'm rooting for this to happen. A hug.

[JaneDr-xz]

A really great, clear and thoughtful explanation of the study so far. Thank you! It's such a privilege to have cutting edge research developments available to anyone who's interested.

[laurengianna]

Sadly I won’t get another CTA because of radiation. I’ll stick to sono. Had a CAC and maybe I’ll do another in a year. CIMT said I was low risk and I’m 57 and a former smoker. But they found a nodule on my thyroid 😫. Had uterine cancer in 2019 total hysterectomy so now I’m worried 🥲. Love the work Nick and Dave do 🙌🏼. On carnivore since December 2023. Feel amazing!

[efsmiley]

I'm LMHR. Keto for 8yrs. Last measured: triglycerides 52, HDL 98, LDL 160. 18.5 bmi. This study is reassuring and fascinating. So looking forward to more studies to come. How exciting for you! How exciting for all of us! Curiosity is key!!

[truthseeker]

Nick… YT must be suppressing your show. There is zero reason why you shouldn’t have at least 1M subs by now! Thank you and keep up the good work!

[jonathansamaroo]

Finished.

Alternative title: "Statin manufacturers hate this one study"

[debjordan]

My LDL at last test in Feb 2024 was 353, CAC score "0". Age 73 female. Not a LMHR. Carnivore 99% over 4 years. Protein 110 grams max. In 2005 my LDL calculated was 138, HDL 65, trigs 83.

[thestrongcarnivoress]

I am a LMHR. LDL 500, BMI 22. Previously BMI was 35.
HDL/Trig ratio 0.8.
I had my CT angiogram to get my CAC. Zero scores across all measures. Cardiologist scratching his head.
Carnivore since Feb 2022.
Prior to that Keto from Dec 2020.
Never sick anymore.

[PhilHugo]

Brilliant content Nick, thanks for everything you guys do for the LMHR community