FDA approval of REZDIFFRA (resmetirom) for NASH/MASH treatment

preview_player
Показать описание

This video describes the approval of REZDIFFRA, which contains resmetirom as its active pharmaceutical ingredient. REZDIFFRA is approved for treatment of liver fibrosis due to NASH (non-alcoholic steatohepatits) or MASH (metabolic dysfunction-associated steatohepatits). REZDIFFRA was approved by the U.S. FDA on March 14, 2024. The sponsor of the NDA was Madrigal Pharmaceuticals. Resmetirom's mechanism of action is as a thyroid receptor-beta agonist with selectivity for the beta receptor over the alpha form. Efficacy, ADME/PK, and key safety risks of REZDIFFRA are discussed.

This video was created for academic purposes. The creator of the video has no financial stake in the drug sponsors or relationship with the FDA.
  1. Chem Help ASAP
  2. Chem Help ASAP
  3. Chem Help
  4. Chem ASAP
  5. ASAP chem
  6. medicinal chemistry
Рекомендации по теме
FDA approval of 0:10:26

FDA approval of REZDIFFRA (resmetirom) for NASH/MASH treatment

Rezdiffra - The 0:01:22

Rezdiffra - The First FDA Approved Drug for an Advanced Form of Nonalcoholic Fatty Liver Disease

FDA Approves Rezdiffra 0:00:46

FDA Approves Rezdiffra (Resmetirom) for Non-Alcoholic Fatty Liver Disease

New Fatty Liver 0:04:11

New Fatty Liver Medicine FDA Approved | Fatty Liver Treatment | Rezdiffra Resmetirom

Madrigal Pharma’s Rezdiffra 0:00:37

Madrigal Pharma’s Rezdiffra Gets FDA Approval as First Treatment for Fatty Liver Disease NASH/MASH

#Resmetirom : New 0:07:52

#Resmetirom : New FDA Approved Drug for Fatty Liver

Naim Alkhouri, MD: 0:08:44

Naim Alkhouri, MD: Resmetirom Has Been a “Game Changer” in MASH Since FDA Approval

Resmetirom: The First 0:23:36

Resmetirom: The First FDA-Approved Therapy for MASH

What is Resmetirom 0:03:06

What is Resmetirom and How Does it Work to Treat MASH?

First Fatty Liver 0:05:06

First Fatty Liver Medication approved by FDA | New medicine | Rezdiffra | Madrigal | Resmetirom

Approval of Rezdiffra 0:02:11

Approval of Rezdiffra (Resmetirom) by FDA for Advanced NASH Treatment.

ENG_First Fatty Liver 0:04:11

ENG_First Fatty Liver Medication approved by FDA | New medicine | Rezdiffra | Madrigal | Resmetirom

REZDIFFRA (Resmetirom): The 0:03:25

REZDIFFRA (Resmetirom): The Next Big Thing in Liver Disease Treatment

From Trials to 0:07:13

From Trials to Triumph: 2024’s FDA approvals

How the Major 0:05:36

How the Major Milestone in NASH Treatment Revealed

FDA approves first 0:01:03

FDA approves first drug for NASH liver disease

Resmetirom: Breakthrough Treatment 0:01:26

Resmetirom: Breakthrough Treatment for NASH – A New Hope for Liver Disease!

Rezdiffra for Fatty 0:01:55

Rezdiffra for Fatty Liver?!?

First Real-World Resmetirom 0:03:29

First Real-World Resmetirom Data Provide Insight Into Use in Clinical Practice

REZDIFFRA A New 0:02:04

REZDIFFRA A New Dawn in NASH Treatment Dr Bao's Clinic

Unmet Needs in 0:01:03

Unmet Needs in #MASH, Even After Resmetirom Approval

GLP-1 RAs for 0:03:56

GLP-1 RAs for MASLD: Real-World Data Suggest Benefits

Fatty Liver Disease 0:00:54

Fatty Liver Disease #fattyliver #rezdiffra #madrigal #drugsafety

Approval of First 0:01:47

Approval of First NASH Medication!

Комментарии
Автор

Thank you very much for making this video. You're one of the only channels that (I'm aware of) covers medicinal chemistry in an accent that I can understand easily. Please keep up the great work as long as you are able.

usernamehere
Автор

resmetirom also has liver-loading property, about 8:1 liver to plasma ratio in mice. Great video!

joshyu
Автор

Is resmetirom for NAFLD or for NASH or for both?

mihirpal
join shbcf.ru