CNG Channel-Related Retinopathy Explained (Phototransduction in Retina) | Originals

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Welcome to Science With Tal!

In this video, we will cover the phototransduction pathway in the retina and discuss what a mutation in CNG channels can lead to in cones and rods. We will also briefly cover gene therapy and how this treatment could help cure diseases caused by CNG channel mutations.

To improve the quality of my content, I highly value the feedback from the viewer so do not hesitate to give any feedback in the comment section.

TIMESTAMPS

0:00 Introduction
0:15 Retinopathies & Photoreceptors
1:29 Phototransduction (dark)
2:07 Phototransduction (light)
2:50 CNG Channels Structure & Mutations
3:59 Gene Therapy
5:22 Conclusion

RESOURCES

Here is a list of the resources that I’ve used to produce this video. (Author(s): title resource)

- Eric Kandel: Principles of neural science (6th edition)
- Gerhardt: Biology, Pathobiology and Gene Therapy of CNG Channel-Related Retinopathies

To have more information on these resources, you can refer to the conclusion section where a more formal citation is provided.

CREDITS

Writing: Tal Klimenko
Voice: Tal Klimenko
Animations: Tal Klimenko
Drawings: Tal Klimenko
Editing: Tal Klimenko
Introductory jingle: Thierry Du Sablond

Special thanks to Justin Mezzanotte for helping me with various elements in the production of this video.
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All your videos are superbly well-made and really thoroughly explained! Thank you so much :)

kanefrieden