Clearing Soluble Mediators of Cancer with Nanots - Lou Hawthorne at Longevity Summit Dublin 2023

Soluble factors play a key role in cancer, multiple sclerosis, vascular aging, and many other diseases. Antibodies and drugs targeting those factors have struggled in trials due to cross-reactivity with cell-anchored forms of the same biomolecules. Conversely, the depletion of such targets via apheresis displays many-fold greater efficacy, yet faces practical barriers to deployment. Lou Hawthorne reviewed the remarkable potential of nanots – synthetic “molecular sponges” deliverable by routine injection – to combine the benefits of both approaches.

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[haroldkatcher]

Clever Lou. Good to see your still at the top of your game.

[MichaelMerritt]

Incredible. I can’t wait to see what comes of this.

[squamish]

The research into blood factors, like exosome therapy, shows crazy promise for near-term therapies. It's strange that all the old myths about blood and rejuvenation turned out to be right.

[SirTenenbaum]

I remember NaNotics' presentation from last year, and I'm thrilled to see they've established partnerships to continue development and clinical application.