Discuss the Development of Ventricular system from brain vessicles (Lateral ventricles)

Anatomy
The pair of lateral ventricles are the largest of the four ventricles in the brain. They are located in the largest part of the brain, the cerebrum. The third ventricle is in the diencephalon, located in the center of the brain. The fourth ventricle is located in the hindbrain.

Each lateral ventricle, one on each side of the brain, sits in a “C” shape. Each side connects to the third ventricle by the interventricular foramina. The fourth ventricle is diamond shaped and sits below the third ventricle. The cerebral aqueduct connects the third ventricle to the fourth.

Anatomical Variations
A number of developmental anomalies can impact the ventricular system.

Congenital hydrocephalus occurs when the brain fails to develop correctly in utero. The condition is marked by a disproportionally large head size due to the buildup of excess CSF in the ventricles. Pressure from the extra fluid can damage the brain and impair brain function.

Hydrocephalus can also occur in children and adults due to trauma, infection, stroke, and tumors. Risks for congenital hydrocephalus include maternal infections in the mother like toxoplasmosis or syphilis, other congenital neural tube malformations, or a genetic defect.

The most prominent symptom is an enlarged head, but other symptoms may also be present. The fontanelle (soft spot) on a newborn’s head may bulge, the baby may be irritable, sleep too much, vomit, or feed poorly.1

Neural tube defects are congenital malformations of the brain and spinal cord. They occur very early in pregnancy. The most common neural tube defects are spina bifida and anencephaly.

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