Diffusion tensor imaging (via MRI) of the heart

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Dibb, R., Xie, L. & Liu, C. (2014). Magnetic Susceptibility Anisotropy of the Myocardium. In: Proceedings of the 22nd Annual Meeting of ISMRM, Milan, Italy. 2014, p. 627.

Synopsis

The magnetic susceptibility of myocardium is anisotropic and is associated with myocardial organization. We determined the relationship between the magnetic susceptibility and the DTI-based fiber orientation of myocardial tissue. The origins of the observed bulk magnetic susceptibility anisotropy in myocardium can be related to the microscopic anisotropy of peptide bonds in myofibrillar proteins. In MRI, this susceptibility anisotropy is enhanced by the use of contrast agents. Given the high-resolution capability of gradient echo phase, imaging susceptibility anisotropy of the heart would aid in assessing myocardial fiber integrity and alterations induced by cardiac diseases and disorders.
  1. Luke Xie
  2. Magnetic Resonance Imaging (Diagnostic Test)
  3. Diffusion MRI
  4. Heart (Anatomical Structure)
  5. Medical Imaging (Field Of Study)
  6. Cardiac Muscle (Anatomical Structure)
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