Understanding Protein Sorting: Cellular Transport Mechanisms Explained

In this video, I look at protein sorting.

Proteins are primarily synthesised on ribosomes in the cytosol, with some exceptions in the mitochondria. While many proteins remain in the cytosol, others must be transported to specific organelles, a process regulated by sorting signals. These sorting signals, essentially amino acid sequences, act like 'postcodes' directing the proteins to their correct destinations within the cell. The sorting signals fall into four categories: N-terminal signals, Internal stop-transfer sequences, *Internal second signal sequences and C-terminal sequences.

In the video, I also describe the three main types of protein transport (Gated transport, Transmembrane transport and Vesicular transport.

Additional Resources
This video was produced with help from the following resources:

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