Urine Concentration and Dilution | Countercurrent Multiplication

#urine #urinetest #drnajeeb #medicines #pharmacology #medicaleducation #drnajeeblectures

Urine Concentration and Dilution | Countercurrent Multiplication

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(0:00-14:46)
Concepts of Hypo- & Hyperosmolarity; understanding the purpose behind urine concentration and dilution by the kidney.

(14:47-28:35)
Mechanisms of concentration and dilution of urine:
1-Medullary Interstitial Hyperosmolarity (MIH) [Cortico-Papillary Osmolar Gradient]; outline of its mechanism of production and maintenance.
2-Role of ADH as the second mechanism of concentration & dilution of urine.

(28:36-54:50)
Mechanisms of concentration and dilution of urine continued:
1-Development of Medullary Interstitial Hyperosmolarity (MIH); Counter Current Multiplication Mechanism.

(54:51-1:03:26)
Development of MIH continued; Urea Recycling in Renal Medulla.

(1:03:27-1:10:47)
Maintenance of Medullary Interstitial Hyperosmolarity (MIH); Vasa Recta's Counter Current Exchange Mechanism/System.
Comparison of Counter Current Multiplier & Counter Current Exchanger System.

(1:10:50-1:28:55)
Mechanisms of concentration & dilution of urine continued:
2-Role of Anti Diuretic Hormone (ADH); enhancing water permeability in last part of nephron.

(1:28:56-1:47:40)
Recapping the concept of concentration & dilution of urine with the help of an example of a person's thirst and water intake in differing environments; emphasis on effects of ADH on the nephron.

(1:47:41-1:57:57)
Explanation of "Ratio of Tubular Fluid Osmolarity (TF) to Plasma Osmolarity (Posm)" at different points along the nephron; emphasis on the role of ADH.

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[dezangwangchuk]

Erudite explanation. Love from Bhutan. I am a vet Doctor. Thank you for making it crystal clear. Allah bless you always 🙏🙏🙏

[snivellus]

I can’t thank you enough sir for making counter-current mechanism this easy and convenient. I am going to appear in my 1st professional examination and understood this for the first time. Thank you again

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[dickensochieng]

Best lecture of all times, I salute you Dr.... all the way from Nairobi Kenya

[SonaliDas-qqoi]

I understood this mechanism for the first time in my life.. thank you so much sir..take lots of love ❤️

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[AbdulRehman-urwg]

I have read this topic 3times from book i didn't understand this topic.
But from this vid i have understand this topic first time.
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[neershah]

1:10:12 difference between contercurrent multiplier and counter current exchanger system.