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Engineering and Reprogramming Natural Killer Cells for Immunotherapy of Cancer
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Presented By: Sandro Matosevic, PhD
Speaker Biography: Dr. Sandro Matosevic is an associate professor in the College of Pharmacy at Purdue University, and is a member of the Purdue Center for Cancer Research. Dr. Matosevic runs an NIH-funded research program focused on the development and use of cell-based therapies with natural killer cells and CAR-engineered immune cells in the treatment of cancer and holds a number of patents on the engineering and utilization of NK cells and stem cell-derived NK cells in cancer immunotherapy.
Webinar: Engineering and Reprogramming Natural Killer Cells for Immunotherapy of Cancer
Webinar Abstract: Immune cell therapies hold tremendous potential in the treatment of cancer. Among immune cells, natural killer (NK) cells have a powerful innate ability to recognize and eliminate tumor cells. However, in the microenvironment of tumors, especially solid cancers, NK cell numbers are low, and those cells that are able to infiltrate these tumors are dysfunctional. In order to develop NK cell immunotherapies able to overcome aggressive mechanisms of suppression in tumors and enable them to more specifically target various cancers, genetic engineering approaches have been utilized to immunometabolically reprogram and enhance the function and specificity of NK cells against cancer. These genetically-engineered cell-based therapies have been formulated into clinical products and used to treat diverse cancers. ...
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Speaker Biography: Dr. Sandro Matosevic is an associate professor in the College of Pharmacy at Purdue University, and is a member of the Purdue Center for Cancer Research. Dr. Matosevic runs an NIH-funded research program focused on the development and use of cell-based therapies with natural killer cells and CAR-engineered immune cells in the treatment of cancer and holds a number of patents on the engineering and utilization of NK cells and stem cell-derived NK cells in cancer immunotherapy.
Webinar: Engineering and Reprogramming Natural Killer Cells for Immunotherapy of Cancer
Webinar Abstract: Immune cell therapies hold tremendous potential in the treatment of cancer. Among immune cells, natural killer (NK) cells have a powerful innate ability to recognize and eliminate tumor cells. However, in the microenvironment of tumors, especially solid cancers, NK cell numbers are low, and those cells that are able to infiltrate these tumors are dysfunctional. In order to develop NK cell immunotherapies able to overcome aggressive mechanisms of suppression in tumors and enable them to more specifically target various cancers, genetic engineering approaches have been utilized to immunometabolically reprogram and enhance the function and specificity of NK cells against cancer. These genetically-engineered cell-based therapies have been formulated into clinical products and used to treat diverse cancers. ...
Earn PACE Credits:
Labroots on Social:
SnapChat: labroots_inc
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