Altogen In Vitro A375 Transfection Tutorial

Extended exposure to ultraviolet radiation substantially increases the risk of developing melanoma, ranked among the top 10 of the most prevalent cancer types in the US, and top 20 globally. The Skin Cancer Foundation approximates 87,000 novel cases of melanoma will appear per year in the US alone. The A-375 cell line was established from the skin cells of a 54YO female patient diagnosed with malignant melanoma. A-375 cells have since been used as a melanoma model for the development of new medicines in preclinical research. A375 cells are tumorigenic, a suitable transfection host, and exhibit epithelial morphology. Molecular and cell biology research, especially related to skin cancer, has successfully employed A375 cells. Altogen Biosystems offers nanoparticle based optimized A-375 transfection kits available at: