CAR-T cells: the challenges of targeting solid tumors

Justin Eyquem is quite a unique witness of the emergence of CAR-T cell therapies. He did his PhD in partnership with CAR-T company Cellectis. In 2014, he joined the lab of Michel Sadelain at the MSKCC, who co-founded Juno Therapeutics and is now involved with leading CAR-T cell companies such as Fate Therapeutics and Atara Biotherapeutics. Justin eventually established his own lab at USCF and co-founded Mnemo Therapeutics with Michel Sadelain in 2018. In this episode, I asked him about the challenges of addressing solid tumors with CAR-T cell therapies.