Developing gene-editing to prevent corneal dystrophy

OT speaks to Professor Tara Moore about research that aims to develop a gene therapy for corneal dystrophy

[thaddeus]

I have a corneal dystrophy not even sure which one anymore. Had to go for transplant which didn't turn out as clear as I hoped. This is some good stuff, keep on the great work.

[cynthiastogden]

I have Fuchs dystrophy and just had DMEK on one eye. My daughter is 51 and I am concerned she will develop it too. When I had cataract surgery I was not told about my fuchs dystrophy . It developed 3 years later, or it became a real problem.

[themoley]

Whoa, cool. I have posterior polymorphous dystrophy and they’ve identified the gene, so this would be amazing. I don’t plan on having children, partially so I don’t pass this on, but gene editing would be a huge help if I did.

[evanclark]

I have Reis Buckler's syndrome. It's been passed down to every male on my father's side of the family. I would love nothing more than to make it so my future children would never have to deal with this disease.

[gurbinderjandu]

Please can I have more info about this

[khatchant]

My father is suffering from Keratokonus, While serving in Afghanistan he injured his eyes and after than gradually he had eye problems. for now he has 40% vision left in eye, and almost 0% in his right eye, and we were offered morbid solutions by our doctors such as impacted eye removal. Our question is, does your clinic treat or perform anything to repair or fix keratokonus, and is it even treatable at this stage or not?. Any info would be greatly appreciated.

[maridallo]

Is that good news for granular dystrophy patients as well? 😄