SIVA: modelling transwell-based transporter activity assays

Topics Covered:
• Handling of the “raw” in vitro transporter activity data in SIVA
• Obtaining passive and transporter kinetics estimates
• Within assay sampling-replacement corrections

Certara accelerates medicines to patients using proprietary biosimulation software and technology to transform traditional drug discovery and development. Its clients include 1,600 global biopharmaceutical companies, leading academic institutions, and key regulatory agencies across 60 countries.