Part 3: Disseminated Intravascular Coagulation (DIC)

00:00:10 – Definition of DIC
00:00:48 – Causes of DIC – STOP Making New Thrombi
00:01:11 – Pathophysiology of DIC – with explanations
00:03:58 – What the pathophysiology of DIC means clinically
00:04:30 – Organs affected
00:06:28 – Acute vs Chronic DIC
00:07:07 – Specific causes: pathophysiology of sepsis causing DIC
00:07:56 – Specific causes: pathophysiology of obstetric complications causing DIC
00:08:23 – Specific causes: pathophysiology of acute promyelocytic leukaemia (APML) causing DIC
00:09:47 – Investigations of DIC – with explanations
00:11:20 – Treatment/management of DIC

Pronunciation error: we pronounced ecchymoses and eccy-s-moses. We apologise for any inconvenience

In parts 2-6 of the secondary haemostasis series, we shall discuss and breakdown the Need To Know points of the following pathologies
These include
1. Factor deficiency (part 2)
a. Individual factor deficiencies – the haemophilias
b. Vitamin K deficiency
c. Liver disease

2. Pathological activation of the coagulation cascade – so DIC (THIS VIDEO)

3. Excessive fibrinolysis – so over activity of plasmin (part 4)

4. Pathologies that cause thrombophilia including – where a pathologic intravascular thrombus can form (part 5)
Antithrombin deficiency
Proteins C and S deficiency
Factor V leiden
Prothrombin gene variant (20210A)
Hyperhomocysteinaemia
Antiphospholipid antibody

5. Drug reactions (part 6)
a. Heparin-induced thrombocytopenia

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NTK Team.