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The lifespan of bipolar disorder: From treatment naive to treatment resistant - Manpreet K. Singh
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Dr. Singh is a Professor at the University of California - Davis and Director of the Pediatric Mood Disorders Program and the Pediatric Emotion And Resilience Lab (PEARL). Her research focuses on investigating the origins and pathways for developing major mood disorders during childhood. She is also interested in processes that protect and preserve function after symptom onset. Taking a translational medicine approach, Dr. Singh’s patient-oriented research focuses on meeting patient unmet needs through research that aims to accelerate understanding of and treatment in individuals with or at high risk for lifelong mood disorders. She applies cutting edge research strategies to optimize existing therapeutic targets through innovations in trial design, investigations of placebo response, and pursuit of novel therapeutic targets through reverse and forward translation, fast-fail clinical trials, and direct modulation of key brain regions using transcranial magnetic stimulation and real-time neurofeedback. She is also investigating the comparative effectiveness and safety of existing pharmacotherapies and psychotherapies for youth with and at risk for major mood disorders, such as antidepressants, family focused psychotherapy, and mindfulness meditation to reduce mood symptoms and family stress.
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