High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases

Presented By: Aimin Xu, PhD

Speaker Biography: Dr. Aimin Xu is currently a chair professor for the Department of Medicine and the Department of Pharmacology & Pharmacy and the director of the State Key Laboratory of Pharmaceutical Biotechnology at the University of Hong Kong. His work contributed significantly to the understanding of the molecular basis of adipose tissue inflammation and immunometabolic regulators in both metabolic and autoimmune diseases.

Webinar: High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases

Webinar Abstract: Current methods for in vitro diagnosis of autoimmune diseases (ADs) are mainly based on the detection of circulating autoantibodies using specific AD autoantigens. In this webinar we describe the use of the Gibco™ Bac-to-Bac™ Baculovirus Expression System to express 22 recombinant autoantigens in Spodoptera frugiperda 9 (Sf9) cells, with folding and posttranslational modifications matching those of the natural autoantigens in vivo.

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