Navigating the Side Effects and Critical Precautions of Lamotrigine

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The Psychopharmacology Institute is an online platform offering unbiased, practical psychopharmacology updates for healthcare providers, with content updated monthly. It also presents opportunities to earn CME and SA credits.

In this presentation, Dr. Scott Beach delves into lamotrigine side effects and special considerations, including more and less common side effects and skin rashes, especially how to distinguish a benign rash from a concerning one. He points out the characteristics of a concerning rash, dosage recommendations depending on rash characteristics, and the prevalence of rash and HLA markers. Dr. Beach also discusses the protocol after missing lamotrigine doses, its use in pregnancy and breastfeeding, the effect of oral contraceptives on lamotrigine levels, and finally, the overdose effects.

#LamotriginePregnancy #psychopharmacology #LamotrigineRashes #LamotrigineComplexities
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I was on .25 mg for 9 days and developed an extreme rash all over my body. It was really bad.

teshiamcginnis
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Very good Dr
Im Dr kushal from India
Md skin and vd

drsamarthderma
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It's too bad that the risk of a rash is a side effect, given the utility of Lamotragine for different disorders, including (as I understand it) off label anxiety and OCD in addition to bipolar. I wonder/hope that companies could be trying to develop a Lamotragine-type of medication that doesn't carry the rash risk.

MrDcrules