Needleman Wunsch Algorithm|| Dynamic Programming|| Bioinformatics|| Part # 02 (Example)

Uncover the power of the Needleman-Wunsch Algorithm through examples!

In this video, we bring the Needleman-Wunsch Algorithm to life with easy-to-follow examples that will demystify sequence alignment for you. Whether you're a student, researcher, or simply intrigued by the world of bioinformatics, this video is your ultimate guide.

What you'll learn:

A quick recap of the Needleman-Wunsch Algorithm's fundamentals.
Clear step-by-step walkthroughs of the algorithm using actual sequences.
How to create a similarity matrix and apply dynamic programming.
Understanding scoring systems and gap penalties in sequence alignment.

No prior experience required!

Our user-friendly explanations and visual aids will help you grasp the concept and implementation of the algorithm, even if you're new to the topic.

Get ready to witness the Needleman-Wunsch Algorithm in action as we solve alignment challenge and showcase its role in identifying genetic similarities. Don't miss out – hit "Subscribe" and enable notifications to stay updated on our latest videos exploring the exciting field of bioinformatics!

👍 If you find this video helpful, give it a thumbs up and share it with your friends who might find the world of genetics and algorithms fascinating. Feel free to drop your questions and thoughts in the comments – we're here to help!

PDF notes link:

#NeedlemanWunschAlgorithm #SequenceAlignment #Bioinformatics #Genetics #AlgorithmExamples
#ComputationalBiology #DNAAlignment #BioinformaticsTutorial #EducationalVideo

[amanjaved]

This video really helped to understand how to fill in the table. Thank you so much

[edobajoyce]

Whoaa!
Eureka!!
it wasn't so hard after listening to every explanation. Merci!!

[adamoadam]

Isn't
T A - T G A
T A C - G A
with gaps, so the best alignment would be TACTGA ?

[Akam_J_Mustafa]

Well done 👏, this video really helped me to understand NW algorithm matrix. Thanks

[mynameisminhhoang]

Thank you so much, it helps me pass the test. Wish you the best

[victorpeng]

sure is tricky but definitely helped! thank you

[DimitriTrubetskoy]

Great. thanks as well. Now it is clear. Though, you could explain it even a little bit more, with some shifting square for example, and explaining where each number is coming from every time. Even if you said that technically, it's not obvious from the first approach. Thanks anyways

[erikOHsix]

so what is the possible alignment at the end? I can't see it because the "Bio Scholar" logo is in the way

[santiagovega]

hello! I understand that negative values ​​are placed directly as 0, so the first row and the first column are all 0

[UCSRAHULMAURYA]

does match and mismatch scores are pre decided as 1 and -1 or it can be changed?....can match score be assumed as +5 and mismatch as -1??

[justsmileme]

I'm curious if the opening gap penalty and extension gap penalty is different.

[justem_things]

sir i think the value for 5th column and 2nd row is wrong ie., for G and T respectively. please have a look and if not please clear by doubt

[nitehok]

what would be the alignment score and how do you find it?

[Nandhini-sm]

3rd row and 3rd c and t how to 1 please explain that

[nitehok]

I think the traceback path you took and the alignment was wrong, if you go vertical or horizontal there should be a dash on the letter you go towards. Your alignment would be (T A - T G A / T A C - G A) if you choose to go left at 1.