Equivalent Circuit Model Of The Neuron Explained (Capacitance, Resistance, Driving force) | Clip

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Welcome to Science With Tal!

In this clip of the Signal Propagation in the Neuron video, we will discuss how we can model the neuron as an electrical circuit. We will discuss each analog (resistance, capacitance, voltage, current, driving force) and I’ll give further intuition on how to understand these components of the model. You will see here and in the comment section the time stamps associated with each topic that I’ve covered.

Note that the graphs are not up to scale but the general shapes of the curves reflect the true behaviors of the variables in question.

To improve the quality of my content, I highly value the feedback from the viewer so do not hesitate to give any feedback in the comment section.

Timestamps

0:00 Introduction
0:22 Motivation behind the model
1:15 Membrane capacitance & resistance
3:00 Driving force derivation
5:40 IV curve using I = G(V-E)
7:19 Building the circuit
8:55 Derivation of the equivalent circuit model equation
10:15 Note on passive and active signals
12:00 Alternative equivalent circuit model
14:15 Conclusion

Resources used

Here is a list of the resources that I’ve used to produce this video. (Author: title resource)

Dale Purves: Neuroscience (6th edition)
Eric Kandel: Principles of neural science (6th edition)
Alan Hodgkin & Andrew Huxley: A quantitative description of membrane current and its application to conduction and excitation in nerve
Alan Hodgkin & William Albert Hugh Rushton: The electrical constants of a crustacean nerve fibre.

To have more information on these resources, you can refer to the conclusion section where a more formal citation is provided.

Video credits

Writing: Tal Klimenko
Voice: Tal Klimenko
Animations: Tal Klimenko
Drawings: Tal Klimenko
Editing: Tal Klimenko
Introductory jingle: Thierry Du Sablond
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Thank you so much! I have finally understood the driving force after such a long time

cleganshotaway
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I was literally crying over my hw until I found this video. THANK YOU

izzybaipho
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Thank you for sharing this information, ¡it is awesome!

emilioarmandohernandezgarc
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Thank you so much, Jarur, Murshidabad, WB, India🇮🇳.

sajiruddinsk
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Thank you so much for this really really helpful video

nisaylmaz
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T H A N K Y O U SO MUSH THAT WAS SO HELPFUL

panax
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What do you mean we don't know the mechanisms responsible for depolarization?? Do you just mean you introduced it later in a video?

nexigent
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Ok, now Gk isn't constant! So the graph cannot be a straight line I suppose...

Catherinerebekah