Your BLOOD TYPE: ABO and Rh (donuts and sprinkles!) 🐧🩸🩸🐧

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All about blood types - ABO and Rh blood groups. Who donates to whom? How are blood types inherited? What are the medical issues involved with transfusions? DON'T memorize that donor / recipient table - watch this video instead!

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VIDEO DETAILS:

Blood Groups: ABO and Rh
Blood Group Systems
32 human blood group systems are now recognized by the International Society of Blood Transfusion
The most important of these: ABO blood group system and Rh blood group system

Discovery of ABO Blood Types
ABO blood types were discovered in 1900 by Dr. Karl Landsteiner at the University of Vienna
He wondered why some patients died as a result of blood transfusions and others did not
Inheritance

Blood types are inherited genetic traits (like eye color, hair color, etc.)

ABO Analogy: Donuts and Sprinkles
donut = red blood cell
A sprinkles = A antigens
B sprinkles = B antigens
no sprinkles = no antigens (plain donut)

What are the antigens chemically?

Alleles in the ABO System
i = base (plain donut)
IA = encodes A antigens
IB = encodes B antigens

Allele Combinations
ii
IAIA or IAi
IBIB or IBi
IAIB

Antigens and Antibodies
The antigens you have on your blood cells are recognized by your immune system as SELF antigens
If foreign antigens are discovered in your body, antibodies (or immunoglobulins) will be made by B cells of the immune system

Antibody Structure

Antigen + Antibody = agglutination reaction
Agglutination = the clumping of particles
Latin: agglutinare meaning 'to glue'

Mixing of all blood groups and the result

KEY: CANNOT transfuse if foreign antigens are introduced!!!

The Rh Antigen
Inherited in Mendelian fashion!
Medical issue: Rh- mother and Rh+ fetus
Good News...
Rho(D) Globulin Treatment
("RhoGAM")
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This lady has the sweetest voice ever.. I'm expecting her to say she made cookies for me at the end of the video or something.  Very helpful!! Thank you!!

calbatal
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You explained this better in a few minutes than I have understood in 2 weeks of study. THANK YOU!

amandainskeep_shelton
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Discovered your videos today and binge-watched !
I am a 70 year old PhD and you have explained things
that I never understood, but just memorized !
Your deep understanding allows for an elegant and entertaining presentation.
I will recommend you to my grandchildren and my AARP friends as well.

lynngillikin
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Why can't my lecturers sound this kind and enthused 😂 so good.

JaydenOrdner
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I have had this explained to me 1, 000 times by different professors, and I have always struggled with antigen vs antibody, and it's been so frustrating. You are the only who has explained this in a way that I can actually understand! Thank you!

dinatorres
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Probably the BEST educating video. Education systems should follow similar concepts!

yasserabood
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thank you so much. i have a blood test tomorrow and was freaking out with all the crap i had to learn on top of this chart and you just made it soooo easy! THANK YOU! nursing school is so hard but people like you who make these videos make a major difference in helping me study

jarrodpairgin
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"they have a little..depression"
me: "lol, same."

jiannaanai
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"Look at him, he's so positive" xD Love your videos, Penguin Prof! Thank your for taking the time to help us out :) Have a wonderful day!

AndromedaMarina
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I'm so getting an A+ on my Bio final. In fact, it's even in my blood.

avi
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I'm in my first year of grad school working towards my Family Nurse Practitioner degree and I love watching your videos. You make it so easy to understand! Keep it up!!

elizabethsaumur
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This is right up there (if not better) with the best - Khan Academy, Bozeman Science, Crash Course... thanks for your amazing work! 

kreaftw
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You have saved me with my human bio test! Thank you so much!!! It was very easy to understand, much more than the strange worksheets given in class. Thank you again!

clairebear
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I’m not even from the medical field but this was so easy to follow and learn. Great job explaining the subject!

Buddles
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I never taught that I would understand blood typing until I stumbled upon your channel. After watching ur content, I subscribed straight up. God bless you.

bintage
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I love your lecture - you enthusiasm and up beat personality in your voice make it much more fun learn.

cu
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T'was just so impressive! The explanation, clarity of the video and your voice was just perfect!!! Thank you so much! It helped a lot!😄😄😄

gaurangeemhadgut
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My Instructor sent me the link to your video and I'm glad that she did. The reading material was confusing and now this makes it make sense. The video was very informative, helpful, and helpful. Thank You.

pamilynl.turner
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Best analogy ever, donut with sprinkles .... Thank God we have teachers like you out there...

ingridramey
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OH GOSH! This is the best video ever for understanding this! And her voice is so soothing thing and mellow about the whole thing! I came here freaking out about this paper I have to write about the inheritance of blood types and I feel so much more confident now.

Thank you!!!!

Stacymc
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