Myology - Skeletal Muscle Contraction

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[saramansour]

I’ve managed to struggle less, decrease my time consumption on a single topic, prepare the perfect notes for any upcoming exams, i showed less effort watching your videos than studying alone but still managed to get a better outcome and i feel so grateful towards you.

[BigStuW]

Note that calcium ions do not enter the t-tubule from the SR.
Calcium ions diffuse out of the SR through the Ca-release channels into the sarcoplasm where they directly initiate the cross-bridge cycle upon binding to troponin on the thin filament

[courtneythefrogologist]

Technically the t-tubules are dips into the muscle fiber, from the sarcolemma, they don't run around the myofibril. Although you are correct that the SR are around each myofibril. The SR and the t-tubule are in contact through the DHPR receptor on the t-tubule and the RYR receptor on the SR. When the voltage runs down the t-tubule the DHPR response to the voltage by changing 'shape' which in turn cause the RYR to open to allow Calcium to flow into to cytoplasm. Calcium never enters the t-tubule. Calcium binds to troponin which is located on the thin filaments.
 I should add that your videos are my go to videos that I suggest to my students. Nice artwork!

[RunningToNotBeSeen]

It's amazing to think that all this happens EVERYTIME you use a skeletal muscle. It's almost overwhelming to wrap your mind around. 

[claramaria]

Dude, I have no words to thank you for these videos. Not only you ilustrate the information gathered in books and classes perfectly but you also do it in a very didatic way. You've got an amazing talent, keep it on!

[FartyHarley]

"Sarco" not "sacro", and the transverse tubules are invaginations of the sarcolemma, so the Ca ions do not release into the t-tubules, but the voltage-gated protein receptor between the SR and the t-tubule releases the Ca into the sarcoplasm through the sides of the gate i.e. The gaps in the triad. Apart from that, love the drawing.

[jingjingliu]

after struggling and leaning muscle contraction for the whole day, I finally got a clear head after your demonstration!! THANK YOU!!

[bethanybeck]

Can you just take all my notes for me? This is beautiful and it makes more sense than anything my professor was trying to say...

[klp]

Great Videos!
What We could not understand from hours long lecture you have explained in short time.

[saramansour]

I’ve been watching your channel for a while now to help me with my study, I’m a medical student and I’ve been having a hard time making sense out of my professor bad explanation, with you amazing help I managed to pass my exams only by watching your videos and only reading my materials, thank you so so much hope to see more of your videos coming to help all of the medical students out there in need wish you best of luck.🤍🙏🏻

[halffull]

Thank you much for taking the time and effort to put these videos together. It has definitely made this material easier to visualize and understand.

[mariellalavado]

Thankyou Armando. Since I found you on youtube, it was easy to pass my exams at medical school.

[oSilentVeterano]

Your drawings are BRILLIANT. Makes me understand it much easier. That's the thing about exam boards they teach you about the important things but never go into detail like you did.

[missc]

Very informative and beautifully illustrated. Thank you for posting!

[kimburlie]

You just saved me. I haven't understood this, until you explained it with your drawing. I just might get a good grade on my final exam. I can't thank you enough. I am going to share this video with my instructor.

[jeanettesummerville]

This was the amazing. I don't often see videos that are are so easy to follow and simplify the complicated process as well as you did. Thank you.

[marilynmata]

This was amazing! you explained this so well! I did not understand in an hour and thirty minutes in lecture! i understood it in 7 minutes!! thanks

[pantelispanas]

This series of medical videos is an excellent way of conveying information. Great and innovative effort. Keep up the good work.

[rkristjansson]

Great illustrations, and it makes it so much Easier to understand. thank you Armando

[trevasaurusrex]

You've created a very practical and enjoyable way to learn biology. Very Well Done!