Synthesis of Drugs: Lasmiditan

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In this video I’m going to talk about the synthesis of Lasmiditan, an orally bioavailable selective serotonin receptor agonist discovered by Eli Lilly and Company and approved by the FDA for the acute treatment of migraine in adults.

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As somebody mentioned, there is an error in the structure of the Buchwald-Hartwig product in min 3:04. Instead of diphenylamino it should be diphenylmethanimine. Thanks a lot to the person who found out. 😉

NROChemistry