Botulinum Toxin & Tetanus Toxin Mechanism

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Botulinum and Tetanus Toxin Mechanism

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Tetanus neurotoxin acts mainly at the CNS synapse, while the seven botulinum neurotoxins act peripherally. Clostridial neurotoxins share a similar mechanism of cell intoxication: they block the release of neurotransmitters. They are composed of two disulfide-linked polypeptide chains.
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