Understanding Multiple Myeloma (Multiple Myeloma Explained Clearly)

A look at Multiple Myeloma (including MGUS), covering pathophysiology as well as signs and symptoms of multiple myeloma (CRAB criteria). Also includes the diagnostic criteria and treatment.

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Video Timestamps:
0:00 What is Multiple Myeloma?
0:21 Multiple Myeloma Pathophysiology
1:34 Plasma Cell Dyscrasias
2:57 Multiple Myeloma Symptoms
5:59 Multiple Myeloma Causes & Risk Factors
6:51 Multiple Myeloma Diagnosis
7:11 Multiple Myeloma Diagnostic Criteria
7:38 Multiple Myeloma Treatment

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Please remember this video and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.

MUSIC IN THIS VIDEO:
Sound Effects - Zapsplat

IMAGES:
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[connerdixon]

My mom died from Multiple Myeloma when I was 17. 3 years later it still hurts me more than anything. I miss her more than anything in this world. I can’t even begin to describe how much I hate this disease. She was the most beautiful person I’ll ever know. Thank you for this video, and thank you for helping me to understand this disease. It was hard knowing there was nothing I could do to help her. Man it hurts thinking back. Thanks again for the video man.

[keiracoven]

Watching this because my mom was just diagnosed. She seems to have a positive but strange prognosis where she's still stage 1, has not developed bone lesions, and her organs are still functioning as expected, but over 70% of her plasma cells are abnormal. She also doesn't seem to have some of the more high risk mutations. The doctors seem positive she will live for many more years but I'm terrified. I know very few people want to lose their mom, but god I really can't imagine losing her as young as she is. I'm trying really hard to stay positive for her but honestly, fuck cancer.

[ShikhaSingh-wjvz]

I am from India and i am a nursing officer 💖 your study material is so good thnku ....

[DrRoton-lnbr]

You are the best.
We want more lectures on various important tropics.

[sadesongbird]

Love the detailed video. Using it on my page to bring awareness to different cancers every month. Will post the link to this video. Sometimes you have to look for the information cause ppl either dunno where to look and don't at all. Thank you.

[Derebaut]

I've recently come across your channel. I graduated veterinary faculty and I'm studying medicine and still working as a vet. Your videos are extremely helpful and one of the best of this kind on youtube. It's a pleasure to watch them and they're full of new information. i hope you'll carry on with internal medicine videos. Keep up the good work!

[janeEAV]

Thank you so much for clearly explaining this disease that my husband has recently been diagnosed with. He is being treated with daratumumab, dexamethasone and lenalidomide, which you mention. Thank you♥️

[Smooshes]

Thank you, I now understand more clearly and will share with my inexperienced GP.

[BaldEagleVince]

Thanks for the clear explanation. I have just been diagnosed with multiple myeloma this week so I am still processing the details of my condition and potential prognosis. I have a large growth on my skull 💀 which has been the 1st indication of the disease, which has not yet been determined by Stage yet. I am to have a biopsy this week so I will find out more after that.

We shall see 👀 how it goes...🙏

[JeanSlimmon]

Thank you so much for this informative article .
I have been receiving treatment for the past two years and am coping very well.I appreciate the treatment I'm receiving. The only problem I have is fatigue but I'm learning to cope by pacing myself.Thanks again for the article

[docimma]

Please offer explanation of how MM causes paralysis. You only briefly mentioned spinal lesions and radiculopathy.

[johant]

thanks for this video.. I was recently told I have MGUS. I had a blood test for something completely unrelated which showed up an elevated level of paraprotein. I have had the x-rays, ct scan and bone marrow biopsy. I'm currently on 4 monthly watch and wait.

[ManuelParodiRamos]

Hi, very good job. I went directly to your profile to check if you had those treatment options (immunomodulatory, proteasom inhibitors etc) explained in other videos. That´ll be great.
What program you use for the animations?

[montazaraldujeili]

can you make videos about lymphoma and leukemia please

[albertcarello]

Constant low hemoglobin is an early sign. If your hemoglobin is well below 14. Mine is from 9.8 to 10.2. My doctor is taking this very overly lightly and has become constantly unconcerned being more preoccupied with COVID! I'M REALLY PISSED!!!

[chellesswell]

Greetings all. I am currently in the MGUS Phase. I had a cleat pet scan back in December, but I've been having consistent pain in my back and legs recently. I'm wondering has anyone had the experience of being diagnosed with smoldering MM or MM without any evidence of lesions. As always, any input or insight is greatly appreciated. Be blessed and well. Thank you!

[cecillemarie]

This guy’s pronunciations are great, except i found it funny how weird he pronounced the words, “skeletal” and “status”.
Other than that, great teaching on the subject.

[alhaddi]

إن كان تابع أحمد متوهباً
فليشهد الثقلان أنني وهّابي