Induced Pluripotent Stem Cell iPSC

The development of this video was funded under NIE Incentivsing ICT Use Innovation Grant to Asst. Prof. Chen Zhong (I3G 02/16 CZ).

We often hear in Chinese myths that there was an elixir of eternal life that would grant the people who drank it immortality. Of course it was brushed aside as a myth but what if I said that this could actually be a reality in the years to come.

[alyssagiberson]

Thank you so mcu for this video I was so confused but the way you broke it down into more easy to understand information made it 100% easier to understand.

[Khalid_Khan]

I was very confused before, after this video I have no confusion. Thank you so much

[Tanander]

I enjoyed the video, in particular I especially like the analogy of the flour, cake and cookie which aptly portrays the definition of pluripotency. The video also concisely summarises the concept of iPSC, looking at its definition, advantages and limitations. However, I still have reservation about using iPSCs to grow a fully functioning organ which replace damaged or failing organ. Well perhaps, this might happen many decades down the road but for now, the research community has made some progress by growing liver buds using iPSCs which means there is still a long to go before a whole, working organ could be synthesized using iPSC. Also, hopefully, in future, when such technology is successful, it would become more accessible for the people, and not just for the privileged.

[lgdchghd]

This was an awesome video. Concise, clear, and informative.

[bettynelly]

Thanks for the straight forward explanation and great visualization! Keep up the good work! Proud of Singapore!

[elew]

Amazing video, explained everything but didn’t make it complicated!

[omerkhalid]

well done guys
It's a wonderful effort
keep up the good work

[GoingtoHecq]

We should be using this a lot more already. The costs of treating diabetes and failing kidneys are huge compared to any cure.

[alexanderrosenbergjohansen]

This video was really good, thank you!

[yanfanglow]

The way that the video was put together enabled me to understand induced pluripotent stem cells much better. Although it did not list down the minute details, it provides me with an overview that scaffolds my understanding when reading up on this topic.
Indeed, the induced pluripotent stem cell seems promising, however, more research needs to be done to understand this complex technique. Such as the exact formula to differentiate these stem cells into functional organs, and possibly, epigenetics issue.
Perhaps some ways to improve this video would be to introduce the different types of stem cells, (such as adult stem cells, embryonic stem cells) and make a comparison amongst them.

[moistschmeckles]

There is a mistake in this video: when explaining the risks and limitations of iPSCs you showed an erythrocyte being turned into an iPSC, this is not possible since RBCs do not have a nucleus (since we're not frogs). RBCs are lipid packs filled with hemoglobin, it doesn't need a nucleus

[bettynelly]

despite the good presentation - there's a typo at around 3:31 - should be "diabetes" instead of "daibetes" - thank you!

[blainefiasco]

Um, so why is the world not freaking out about this and throwing money at it?

[maartenkeus]

What I always think when people start to worry about custom babies, is that it takes effort and time and thus money to figure out which genes best to edit to change skin/eye/hair color, and even more to figure out how to do it safely of course, so.. who is gonna pay that funding? Who cares about eye color when you can use the same tech to literally cure cancer? Every org in their right mind is gonna want to invest their money into something generally good

[mauricebiron]

Strict controls would not work. You need a medical board that would evolve the rules as the technology advances. Governments would not be able to manage that properly.

[TheConshuscriterion]

Is this process with iPSCs feasible for say regrowing teeth??!

[khuzaymahrasheed]

3C:1 Cell differentiation

Monohybrid & Dihybrid Crosses - PPT

Gene Linkage and Genetic Maps


All of our cells contain the same set of chromosomes hence same genes. For example, the gene that codes for the protein insulin is found in all body cells. However, we only find insulin being produced in pancreatic cells, specifically in the islet of Langerhans. Why do you think so? Include the term ‘cell differentiation’ and ‘gene expression’ in your answer.

When the stem cells are produced, cell differentiation occurs, which then causes different types of cells to produce more proteins that are specific to its cell type. The insulin is moreover an example of gene expression as the insulin gene is being expressed specifically in the pancreas.

What is meant by housekeeping proteins?

They are proteins that are found in the structure of the cell as they are involved in the basic functions of a cell or the set of cells in an organism.
Example: proteins that are included in the structural proteins of the membrane and the enzymes needed in cellular respiration

Blood type is a trait that is determined by multiple alleles (more than 2 variants). What are the alleles of blood type?

Alleles are A, B and O, codes for the antigens on red blood cells. Alleles A and B are codominant, and O is recessive.







Look at this figure. Why both antigens A and B are expressed in Group AB? List all the possible genotypes and phenotypes of blood types.

Phenotypes
Genotypes
Blood Group A
OA or AA
Blood Group B
OB or BB
Blood Group O
OO
Blood Group AB
AB

yBoth A and B are expressed in the

[سارةمصطفى-فت]

How i can getting full scribt writing in english?

[heidiroy-boy]

All i know is im in severe lower back pain for months now and finally got in to see the spinal surgeon and he wants to fuse my spine !! Shit..after reading the questions and comments on google search ..im like NO WAY..its terrifying..there HAS to be another way..like stem cell replacement

[thegamechanger]

Yes, he used that method. I can cured the born girl.. thanks