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Approach to bleeding disorders - causes, pathophysiology and investigations

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Bleeding disorder can be either due to a problem in primary hemostasis or secondary hemostasis. Primary hemostasis related bleeding disorder are due to problems with platelets - either reduced production, increased consumption or increased destruction. Secondary hemostasis related bleeding disorders are caused by problems with the clotting factors - either a deficiency or presence of an inhibitor against the clotting factor. aPTT and PT are investigations used to see how effective the clotting factors are at forming a clot. A prolonged aPTT or PT means that the person has a tendency to bleed.
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Bleeding disorder can be either due to a problem in primary hemostasis or secondary hemostasis. Primary hemostasis related bleeding disorder are due to problems with platelets - either reduced production, increased consumption or increased destruction. Secondary hemostasis related bleeding disorders are caused by problems with the clotting factors - either a deficiency or presence of an inhibitor against the clotting factor. aPTT and PT are investigations used to see how effective the clotting factors are at forming a clot. A prolonged aPTT or PT means that the person has a tendency to bleed.
Support me:
Social media:
Resources:
You can send me mail:
📫 PO BOX 166, Randwick NSW 2031, Australia
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