NETWise Episode 4: Nuclear Medicine for NETs: PRRT- (See Episode 28 for the Updated Version)

This episode of NETRF’s NETWise podcast discusses Peptide Receptor Radionuclide Therapy (PRRT) a targeted form of radiotherapy approved in the U.S. in 2018. Listen in to hear others explain what it is, how it works, and who is most likely to benefit from PRRT. This therapy relies on a tumor’s expression of somatostatin receptors. We explain what they are and how to know if you have them.Then, we’ll take an objective look at the success rates for this therapy. What does research, like the NETTER-1 study, tell us about outcomes for this form of treatment? To give you information about both the pros and cons of PRRT, we will also discuss the potential side effects, from mild to serious. To give you a sense of what it is like to undergo PRRT, we’ll talk with multiple patients about their experience with the procedure itself, as well as the radiation safety precautions patients should take immediately following treatment. Finally, we look to the future asking about some of the new therapeutic directions PRRT is taking.

To download a copy of the transcript for this episode:

Link to the updated episode:

To listen to other NETWise episodes:

NETWise is a podcast featuring neuroendocrine cancer experts and patients, produced by the Neuroendocrine Tumor Research Foundation (NETRF) in Boston, MA, USA.

[elainestephens]

These first 4 episodes have been incredibly informative and helpful … NET was a diagnosis in the family … we are just learning about it, and understanding the diagnosis, terminology, processes and procedures is invaluable to all family members involved, in my opinion.

[hamidabadi]

Hallo...am about to undergo PRRT therapy in India

[shabbarvejlani]

There are multiple regions in the dotanoc pet ct scan which get lit. Given lu-177 dotate therapy works similarly, how is it ensured that they bind to cancerous cell only and not other kind of cells which too have somatostatin receptors(that is the ones which show up in the scan)?

[anthonydomanico]

Great series so far. I’m hoping to hear you really get into the weeds on some of these topics as most of the sources of info on Nets is relatively basic and dumbed down for the patient. We can understand the science as well as anyone so I’ve been forced to drink from a fire hose and look to medical journals to get the full picture. Thanks for what you’re doing!

[manikpradhan]

Is it applicable for pnet with eye metastasis