Polygenic Interactions

Polygenic inheritance is defined as quantitative inheritance, where multiple independent genes have an additive or similar effect on a single quantitative trait. Polygenic inheritance is also known as multiple gene inheritance or multiple factor inheritance.
Polygenic Inheritance characteristics: Polygene refers to a gene that exerts a slight effect on a phenotype along with other genes. Effect of a single gene is too small, so it is difficult to detect. Multiple genes produce an equal effect. Each allele has a cumulative or additive effect. Polygenic inheritance differs from multiple alleles, as in multiple alleles, three or more alleles are present in the same locus of which any two alleles are present in an organism, e.g. ABO blood group system, which is controlled by three alleles
There is no epistasis involved, i.e. masking of the expression of an allele of the different locus. There is no linkage or dominance, rather there exist contributing and non-contributing alleles, which are known as active or null alleles respectively
Polygenic inheritance is characterised by the continuous variation of the phenotype of a trait. The polygenic inheritance pattern is complex. It is difficult to predict phenotype
The statistical analysis can give the estimate of population parameters.
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