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Webinar: Big-Data Approaches to Body Weight and Composition
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Organised by Pete Aldiss, University of Edinburgh, UK and Jo Lewis, University of Cambridge, UK
Fundamental to the maintenance of body weight, which is governed by genetic and environmental factors, is the balance between intake and expenditure (energy homeostasis). Whilst genetic studies have identified the brain as having a crucial role in modulating appetite, our mechanistic understanding has arisen from laboratory rodent studies. The proliferation of indirect calorimetry devices provide data on energy expenditure, however, without standardisation, what can we hope to learn from these studies?
June Corrigan (Beth Israel Deaconess Medical Center, Boston, USA) described a big-data approach to understanding metabolic rate in laboratory mice. Similarly, large-scale biobanks combined with genome-wide association studies have shed light on the biological mechanisms driving human adiposity. In the second talk, Katherine Kentistou (University of Edinburgh, UK) highlighted the genetic underpinnings of body composition and obesity.
This is part of the ‘Physiology of Obesity: From Mechanisms to Medicine’ series.
Hear from Early Career Researchers as they explore the molecular, cellular, and neural mechanisms, as well as behavioural aspects, underlying obesity.
Fundamental to the maintenance of body weight, which is governed by genetic and environmental factors, is the balance between intake and expenditure (energy homeostasis). Whilst genetic studies have identified the brain as having a crucial role in modulating appetite, our mechanistic understanding has arisen from laboratory rodent studies. The proliferation of indirect calorimetry devices provide data on energy expenditure, however, without standardisation, what can we hope to learn from these studies?
June Corrigan (Beth Israel Deaconess Medical Center, Boston, USA) described a big-data approach to understanding metabolic rate in laboratory mice. Similarly, large-scale biobanks combined with genome-wide association studies have shed light on the biological mechanisms driving human adiposity. In the second talk, Katherine Kentistou (University of Edinburgh, UK) highlighted the genetic underpinnings of body composition and obesity.
This is part of the ‘Physiology of Obesity: From Mechanisms to Medicine’ series.
Hear from Early Career Researchers as they explore the molecular, cellular, and neural mechanisms, as well as behavioural aspects, underlying obesity.