Local researchers develop chemical compound that could eliminate cancer-induced proteins

암유발 단백질 분해 화합물 개발…새 항암제 개발 기대
An improved anti-cancer drug may be available in the coming years.
A group of local scientists say they've successfully developed a compound called KY-1220 that could potentially eliminate cancer cell growth.
Kim Ji-yeon reports.
A team of Korean researchers said a chemical compound has been developed that could prevent the growth of cancer cells in patients.
The researchers found that the so-called 'KY1220' compound could simultaneously eliminate two kinds of proteins found to trigger cancer.
The team also said it has successfully produced an improved version of the compound that could help open doors for new treatment methods for cancer patients in the near future.

"Early anti-cancer drugs had many side effects and toxins. Moreover, they were too expensive and most of the times not effective, especially when there was a mutation of the cancer-induced protein. Our newly developed compound however, is effective even in cases of mutations."

The team inserted the newly made compound into a group of mice with cancer cells... and found it inhibited the cells by dismantling cancer-induced proteins... including β-catenin and Ras substances, which are prevalent among colon cancer patients.
The team's research, partly funded by the science ministry, was posted online on the renowned Nature Chemical Biology Journal last week.
Kim Ji-yeon, Arirang News.

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