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Christos Kyratsous, Virtual COVID-19 Symposium: August 12 2020
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Christos Kyratsous, PhD, Vice President of Research, Infectious Diseases and Viral Vector Technologies, Regeneron Pharmaceuticals, "Selection, characterization and clinical testing of a fully-human antibody cocktail against SARS-CoV-2 that safeguards against mutational escape"
Dr. Kyratsous presented Regeneron Pharmaceuticals proprietary technology platform for accelerated human antibody based vaccine development. The automated platform utilizes mice to produce human antibodies and was able to reduce the preclinical testing time down from years to several months. By using a cocktail of different antibodies, an increased potency and higher robustness against mutations of the virus is achieved. After successful testing of a COVID-19 vaccine on non-human primates it recently entered the clinical testing stage.
Dr. Kyratsous presented Regeneron Pharmaceuticals proprietary technology platform for accelerated human antibody based vaccine development. The automated platform utilizes mice to produce human antibodies and was able to reduce the preclinical testing time down from years to several months. By using a cocktail of different antibodies, an increased potency and higher robustness against mutations of the virus is achieved. After successful testing of a COVID-19 vaccine on non-human primates it recently entered the clinical testing stage.
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