Metabolism | Urea Cycle

CORRECTION @09:00 Step 1 of the Urea Cycle should be NH3 + HCO3 + 2 ATP forming Carbamoyl phosphate Instead of NH4 + 2 HCO3 + ATP

Ninja Nerds!

In this lecture Professor Zach Murphy will present on the Urea Cycle. During this lecture we will be talking about the oxidative deamination of glutamate giving off ammonia to enter into the urea cycle. We also talk about the various enzymatic processes that occur within the urea cycle. We hope you enjoy this lecture and be sure to support us below!

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[germanengineerbenz]

This youtube channel is so under rated...this guy is amazing.

[onehundredyears]

You should know that you’ve succeeded in your goal; students everywhere now learn from your science (and wisdom 😁).

[tonnern]

There was a small mistake at the start. Glutamate can't travel in the bloodstream because it is charged. What actually happens is glutamate will donate the aminogroup to pyruvate (which becomes alanine), then alanine will travel in the blood stream to the liver. There alanine will donate the amino group to alpha keto glutarate (which becomes glutamate). The end product is the same, but it is not glutamate that travels in the blood!

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[سماء-عط]

يارب يدخلك الجنة من اوسع ابوابها على هذا الشرح

[molitirionMUSE]

Dude you are doing a great work. Heart felt appreciation from biochemists suffering from poor lecturers world over

[meryemmeryem]

U r really the best teacher ever udont know how much u helped me .i really appreciate these huge efforts u just make biochemistry fun and intersting ( a medical student struggling with biochemistry) thanks a lot

[Mia]

After a lifetime of illness & disability from a young age, genetic testing showed Argininosuccinate Lyase deficiency. You have helped me understand how a buildup of ammonia could be causing many of my health issues including brain inflammation & severe fatigue. Thank you!

[icebearsensei]

I'm a medical student and I'm struggling with biochemistry! I never thought that the processes could be amazing. 😆
Watching your videos enable me to understand more. Thanks!

[MsAbby.]

09:00 (commenting for myself to come back to this specific minute)💀🎀

[mariamgeldiashvili]

I am never studying without watching your video about the topic first. You made it super easy and interesting. Thanks!

[kaloncooper]

Zach, I am graduating on Saturday and I can't thank you enough for all you've taught me. Half my science professors have been worthless! God bless you from Nebraska.

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man i wish the professors i pay for were this good at teaching.

[HalaKH]

u have no freacking idea how helpful this video was omg it is so great and u are hella talented great jobbbb thank you so much

[charlottekeys]

What a fantastic video, my son has a urea cycle disorder (citrullinemia) and this video explained everything so well. Thank you

[kaymavel]

The spatial representation of the cycle is so helpful—I always struggle to understand the chemical mechanisms we’re supposed to know when it’s represented as a cyclical diagram without context but this makes sense thank you!!!

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I'm glad I found you..😫😫😫 I always feel like a genius after watching your videos.. Thank

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[hb]

The joy of finally understanding biochemistry! Thank you!