Cirrhosis Overview | Clinical Presentation

What is cirrhosis? Cirrhosis is a disease in which the liver becomes scarred over time from chronic inflammation and liver cell damage. Cirrhosis can be caused by various diseases, with alcohol abuse and viral hepatitis among the most common.

This video discusses the cellular mechanism behind fibrotic tissue generation and the pathophysiology of a cirrhotic liver. It also covers some of the major complications, as well as clinical signs and symptoms.

[Jolley]

man Iam a visual learner and you help tremendously! Thank you to all nursing students out here with little to no money and you still put out great content! Thank you so much

[jeongna]

Thanks for reuploading this, i don’t wanna have to pay cuz i'm broke af

[mayanksonagara]

You guys are doing hell of a great job.i want more of your work, it's easy to understand by your videos.

[rahulnamaste]

My Papa is now free from this disease. He is in heaven. This disease took him last month.

[ggvmcjy]

Thank u my heroes Osmosis, best ever visual teaching, that is my way is learning, 💞💖👏

[natm]

You explained this better than my nursing prof. Thank you so much!

[JS-vrrc]

If you know someone who is drinking heavily, stop them. I had a grandparent who went through this. Without a lot of pain meds the strongest people you know will be begging for relief. It is debilitating.

[angelsofiraq]

Good choice medscape to pick osmosis.. Thanx

[aldinmendozaaguilar]

07:59 my understanding was that when hepatocytes suffer necrosis, more ALT would be released into the bloodstream in contrast to AST because of it's dominant presence over AST. I also understand that patients with cirrhosis do to alcoholism will spill more AST compared to ALT to blood because of mitochondrial damage which releases its AST to the cytoplasm, therefore AST is > ALT in blood. My question is, does this apply to cirrhosis in general regardless of how the liver got to this point?

[sushmitagohain]

Wow!! Never seen such an awesome explanation

[itsjustme]

Thanks for explaining particularly the shunting part. I have NAFLD and a benign tumor on my liver, though no biopsy. My boyfriend thinks I have ascites because I lost 6 lbs almost overnight once I saw my weight on the scale. Legs and feet have had chronic pitting edema for 2 decades. I've smoked for 47 years. Hyperlipidemia, hypothyroid, perfect blood pressure, but not for me. Mine is usually much lower 90's/60's. Left sternocleidomastoid muscle collapsed 4 years ago, or got paresis. Now, the right one is impaired, too., and diagnosed with esophageal spasms a decade ago I think maybe diaphragm spasms or breach or small heart attacks, too. Not goiing to thee doctor until I learn as much as I can. Heart is irregular much of the time and borderline tachy. Broken spine and rods in spine bilaterally that goes from T10 to my ilium and I still do my own chores without even aspirin. Code on discharge papers after breaking my spine at that time, according to W.H.O. was "spinal fusion with deforming dorsopathies." I looked it up. Believe me, I look like I've lived, and I have. :D Had cholecystectomy and ERCP to get stones out of bile ducts, suffer incredible abdominal pain. Toes cannot be controlled if I lay my lift cchair back. I even got a bunion after a bad attack. It's tiring. Pretty sure I have some broken ribs. Just trying to learn everything. I want to one day get a Dr. Visit, only for the purpose of diagnosis but not until I can understand what is being said because the notes I took one time said "peritoneal hernia-delineated fats undelineated." It all works together, you know? Dominoes. I'm not even in my 60's.

[Medical_world__]

Two simple test to remember any disease for lifetime....

1st- armando hasudungan video
2nd- osmosis video

[Rori]

This was very well explained and useful, thank you so much!

[Ladyfrancaasareministries]

Thank you for this knowledge shared. Very informative 👏

[mosripaampa]

Went here because of what happened to John Regala... May God Almighty cure him...

[humerashaikh]

I wish i could give u more than a thousand like ...its that good 😍

[ashishsinghal]

Awesome explanation, pls upload more other video to help medical students .

[ichlazulmaruf]

This is the best explanation, thanks!

[howardsix]

WOW.EXCELLENT.WELL DONE a histologist, but explained a lot to me),

[byahenijun]

thank you so much for very informative cirrhosis overview it helps me a lot. thank you in a billion x